ENSDARG00000061231


Danio rerio

Features
Gene ID: ENSDARG00000061231
  
Biological name :tinagl1
  
Synonyms : tinagl1 / tubulointerstitial nephritis antigen-like 1
  
Possible biological names infered from orthology : Q99JR5 / Q9GZM7 / Tubulointerstitial nephritis antigen-like
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 41769135
Gene end: 41829721
  
Corresponding Affymetrix probe sets: Dr.8747.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000081530
NCBI entrez gene - 562116     See in Manteia.
RefSeq - NM_001044977
RefSeq Peptide - NP_001038442
swissprot - Q1LUC6
ZFIN ID - ZDB-GENE-060503-240
Ensembl - ENSDARG00000061231
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TINAGL1ENSGALG00000017715Gallus gallus
 Q9GZM7ENSG00000142910Homo sapiens
 Q99JR5ENSMUSG00000028776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ctsbb / cathepsin Bb / CTSB* / P07858* / P10605* / cathepsin B*ENSDARG0000010105122
ctsc / cathepsin C / P53634*ENSDARG0000010133421
ctsba / cathepsin Ba / CTSB* / P07858* / P10605* / cathepsin B*ENSDARG0000005512021
ctso / cathepsin O / P43234* / Q8BM88*ENSDARG0000005285514
CABZ01050249.1ENSDARG0000009937613
ctsz / cathepsin Z / Q9UBR2* / Q9WUU7*ENSDARG0000004308113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000668  Peptidase C1A, papain C-terminal
 IPR001212  Somatomedin B domain
 IPR008037  Pacifastin domain
 IPR013128  Peptidase C1A
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0030247 polysaccharide binding IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton lacks parts or has fewer parts of type ceratobranchial cartilage , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage shape , abnormal
Meckels cartilage decreased size , abnormal
Meckels cartilage physical object quality , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased length , abnormal
intersegmental vessel immature , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch neural crest cell decreased distribution , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula aplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage mislocalised , abnormal
ceratohyal cartilage posterior orientation , abnormal
ceratohyal cartilage physical object quality , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage morphology , abnormal
ethmoid cartilage shortened , abnormal
ethmoid cartilage aplastic , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage aplastic , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage disorganized , abnormal
ceratobranchial cartilage decreased size , abnormal
ceratobranchial cartilage decreased amount , abnormal
ceratobranchial cartilage agenesis , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel immature , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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