ENSDARG00000101051


Danio rerio

Features
Gene ID: ENSDARG00000101051
  
Biological name :ctsbb
  
Synonyms : cathepsin Bb / ctsbb
  
Possible biological names infered from orthology : cathepsin B / CTSB / P07858 / P10605
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 52886927
Gene end: 52902720
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137726
Ensembl peptide - ENSDARP00000140815
NCBI entrez gene - 569298     See in Manteia.
RefSeq - NM_001110478
RefSeq - XM_005160932
RefSeq Peptide - NP_001103948
swissprot - A0A0R4IUN6
swissprot - A0A0R4IS30
ZFIN ID - ZDB-GENE-070323-1
Ensembl - ENSDARG00000101051
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CTSBENSGALG00000030016Gallus gallus
 CTSBENSG00000164733Homo sapiens
 CtsbENSMUSG00000021939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ctsba / cathepsin Ba / CTSB* / P07858* / P10605* / cathepsin B*ENSDARG0000005512068
tinagl1 / tubulointerstitial nephritis antigen-like 1 / Q99JR5* / Q9GZM7* / Tubulointerstitial nephritis antigen-like *ENSDARG0000006123131
ctsc / cathepsin C / P53634*ENSDARG0000010133431
ctsz / cathepsin Z / Q9UBR2* / Q9WUU7*ENSDARG0000004308122
CABZ01050249.1ENSDARG0000009937620
ctso / cathepsin O / P43234* / Q8BM88*ENSDARG0000005285519


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR012599  Peptidase C1A, propeptide
 IPR013128  Peptidase C1A
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000055120 ctsba / cathepsin Ba / CTSB* / P07858* / P10605* / cathepsin B*  / complex
 ENSDARG00000101051 ctsbb / cathepsin Bb / CTSB* / P07858* / P10605* / cathepsin B*  / complex






 

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