ENSGALG00000030016


Gallus gallus

Features
Gene ID: ENSGALG00000030016
  
Biological name :CTSB
  
Synonyms : cathepsin B / CTSB
  
Possible biological names infered from orthology : P07858 / P10605
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 107829340
Gene end: 107838487
  
Corresponding Affymetrix probe sets: Gga.3854.1.S2_at (Chicken Array)   GgaAffx.21123.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056671
Ensembl peptide - ENSGALP00000061589
Ensembl peptide - ENSGALP00000061047
NCBI entrez gene - 396329     See in Manteia.
RefSeq - NM_205371
RefSeq Peptide - NP_990702
swissprot - A0A1L1RS19
swissprot - A0A1D5PUR5
Ensembl - ENSGALG00000030016
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctsbaENSDARG00000055120Danio rerio
 ctsbbENSDARG00000101051Danio rerio
 CTSBENSG00000164733Homo sapiens
 CtsbENSMUSG00000021939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TINAGL1 / tubulointerstitial nephritis antigen like 1 / Q99JR5* / Q9GZM7* / Tubulointerstitial nephritis antigen-like *ENSGALG0000001771534
TINAG / tubulointerstitial nephritis antigen / Q9UJW2*ENSGALG0000001630031
CTSC / Gallus gallus cathepsin C (CTSC), mRNA. / P53634* / P97821* / cathepsin C*ENSGALG0000001723929
CTSZ / cathepsin Z / Q9UBR2* / Q9WUU7*ENSGALG0000000746221
CTSO / cathepsin O / P43234* / Q8BM88*ENSGALG0000000937316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR012599  Peptidase C1A, propeptide
 IPR013128  Peptidase C1A
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0030574 collagen catabolic process IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0046697 decidualization IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043394 proteoglycan binding IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000030016 CTSB / cathepsin B / P07858* / P10605*  / complex






 

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