ENSGALG00000017239


Gallus gallus

Features
Gene ID: ENSGALG00000017239
  
Biological name :CTSC
  
Synonyms : CTSC / Gallus gallus cathepsin C (CTSC), mRNA.
  
Possible biological names infered from orthology : cathepsin C / P53634 / P97821
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 188310798
Gene end: 188327047
  
Corresponding Affymetrix probe sets: Gga.6390.3.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027816
Ensembl peptide - ENSGALP00000062662
Ensembl peptide - ENSGALP00000059109
NCBI entrez gene - 419014     See in Manteia.
RefSeq - NM_001321554
RefSeq - XM_417207
RefSeq Peptide - NP_001308483
swissprot - A0A1L1RV11
swissprot - A0A1L1RK36
swissprot - F1NWG2
Ensembl - ENSGALG00000017239
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctscENSDARG00000101334Danio rerio
 CTSCENSG00000109861Homo sapiens
 CtscENSMUSG00000030560Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TINAGL1 / tubulointerstitial nephritis antigen like 1 / Q99JR5* / Q9GZM7* / Tubulointerstitial nephritis antigen-like *ENSGALG0000001771519
CTSB / cathepsin B / P07858* / P10605*ENSGALG0000003001619
TINAG / tubulointerstitial nephritis antigen / Q9UJW2*ENSGALG0000001630019
CTSZ / cathepsin Z / Q9UBR2* / Q9WUU7*ENSGALG0000000746218
CTSO / cathepsin O / P43234* / Q8BM88*ENSGALG0000000937315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR014882  Cathepsin C exclusion
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001913 T cell mediated cytotoxicity IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005764 lysosome IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016505 peptidase activator activity involved in apoptotic process IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000034821 LMAN1 / protein ERGIC-53 precursor / P49257* / Q9D0F3* / Protein ERGIC-53 * / lectin, mannose binding 1*  / complex / reaction






 

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