ENSDARG00000061391


Danio rerio

Features
Gene ID: ENSDARG00000061391
  
Biological name :grhl1
  
Synonyms : grainyhead-like transcription factor 1 / grhl1
  
Possible biological names infered from orthology : Grainyhead-like / Q921D9 / Q9NZI5
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 32391056
Gene end: 32426413
  
Corresponding Affymetrix probe sets: Dr.5147.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124180
Ensembl peptide - ENSDARP00000144151
Ensembl peptide - ENSDARP00000124914
Ensembl peptide - ENSDARP00000123737
NCBI entrez gene - 324942     See in Manteia.
RefSeq - NM_001305567
RefSeq Peptide - NP_001292496
swissprot - F8W5A2
swissprot - E7FCE3
swissprot - F8W603
swissprot - A0A286YAF2
ZFIN ID - ZDB-GENE-030131-3665
Ensembl - ENSDARG00000061391
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRHL1ENSGALG00000038495Gallus gallus
 GRHL1ENSG00000134317Homo sapiens
 Grhl1ENSMUSG00000020656Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grhl2b / grainyhead-like transcription factor 2b / GRHL2* / Q6ISB3* / Q8K5C0* / Grainyhead-like * / grainyhead like transcription factor 2*ENSDARG0000006197457
grhl2a / grainyhead-like transcription factor 2a / GRHL2* / Q6ISB3* / Q8K5C0* / Grainyhead-like * / grainyhead like transcription factor 2*ENSDARG0000005834254
grhl3 / grainyhead-like transcription factor 3 / Q5FWH3* / Q8TE85* / Grainyhead-like *ENSDARG0000007855237
ubp1 / upstream binding protein 1 / Q811S7* / Q9NZI7*ENSDARG0000001800020
tfcp2 / transcription factor CP2 / Q12800* / Q9ERA0* / Mus musculus transcription factor CP2 (Tfcp2), transcript variant 3, mRNA.*ENSDARG0000006030619
tfcp2l1 / transcription factor CP2-like 1 / Q3UNW5* / Q9NZI6* / Transcription factor CP2-like protein 1 *ENSDARG0000002949719


Protein motifs (from Interpro)
Interpro ID Name
 IPR007604  CP2 transcription factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002934 desmosome organization IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0008544 epidermis development IMP
 biological_processGO:0048839 inner ear development IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000431 semicircular canal semicircular canal malformed , abnormal
Show

 ZFA:0001617 otolith otolith amount , abnormal
otolith decreased size , abnormal
otolith mislocalised , abnormal
Show

 ZFA:0009366 hair cell hair cell apoptotic process increased occurrence , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , abnormal
neuromast hair cell apoptotic , abnormal
neuromast hair cell desmosome disorganized , abnormal
neuromast hair cell desmosome damaged , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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