ENSDARG00000061974


Danio rerio

Features
Gene ID: ENSDARG00000061974
  
Biological name :grhl2b
  
Synonyms : grainyhead-like transcription factor 2b / grhl2b
  
Possible biological names infered from orthology : Grainyhead-like / grainyhead like transcription factor 2 / GRHL2 / Q6ISB3 / Q8K5C0
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 12234975
Gene end: 12291981
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124302
Ensembl peptide - ENSDARP00000150173
NCBI entrez gene - 100034503     See in Manteia.
RefSeq - NM_001083072
RefSeq Peptide - NP_001076541
swissprot - F7VJQ5
ZFIN ID - ZDB-GENE-060503-719
Ensembl - ENSDARG00000061974
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRHL2ENSGALG00000037687Gallus gallus
 GRHL2ENSG00000083307Homo sapiens
 Grhl2ENSMUSG00000022286Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grhl2a / grainyhead-like transcription factor 2a / GRHL2* / Q6ISB3* / Q8K5C0* / Grainyhead-like * / grainyhead like transcription factor 2*ENSDARG0000005834263
grhl1 / grainyhead-like transcription factor 1 / Q921D9* / Q9NZI5* / Grainyhead-like *ENSDARG0000006139158
grhl3 / grainyhead-like transcription factor 3 / Q5FWH3* / Q8TE85* / Grainyhead-like *ENSDARG0000007855237
ubp1 / upstream binding protein 1 / Q811S7* / Q9NZI7*ENSDARG0000001800021
tfcp2 / transcription factor CP2 / Q12800* / Q9ERA0* / Mus musculus transcription factor CP2 (Tfcp2), transcript variant 3, mRNA.*ENSDARG0000006030620
tfcp2l1 / transcription factor CP2-like 1 / Q3UNW5* / Q9NZI6* / Transcription factor CP2-like protein 1 *ENSDARG0000002949719


Protein motifs (from Interpro)
Interpro ID Name
 IPR007604  CP2 transcription factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0021555 midbrain-hindbrain boundary morphogenesis IMP
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0060561 apoptotic process involved in morphogenesis IGI
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic , abnormal
Show

 ZFA:0000029 hindbrain hindbrain apoptotic , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
midbrain hindbrain boundary absent , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle increased size , abnormal
Show

 ZFA:0000128 midbrain midbrain apoptotic , abnormal
Show

 ZFA:0000135 notochord notochord undulate , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal morphology , abnormal
Show

 ZFA:0001115 trunk trunk shortened , abnormal
Show

 ZFA:0001117 post-vent region post-vent region deformed , abnormal
Show

 ZFA:0001261 ventricular system ventricular system morphology , abnormal
Show

 ZFA:0001617 otolith otolith absent , abnormal
otolith decreased size , abnormal
Show

 ZFA:0007068 otic epithelium otic epithelium decreased thickness , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr