ENSDARG00000062251


Danio rerio

Features
Gene ID: ENSDARG00000062251
  
Biological name :fbxl7
  
Synonyms : A1A5X2 / F-box and leucine-rich repeat protein 7 / fbxl7
  
Possible biological names infered from orthology : F-box/LRR-repeat protein 7 / Q5BJ29 / Q9UJT9
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 21634128
Gene end: 21734733
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000084255
NCBI entrez gene - 569430     See in Manteia.
RefSeq - NM_001080042
RefSeq Peptide - NP_001073511
swissprot - A1A5X2
ZFIN ID - ZDB-GENE-061215-122
Ensembl - ENSDARG00000062251
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FBXL7ENSGALG00000031947Gallus gallus
 FBXL7ENSG00000183580Homo sapiens
 Fbxl7ENSMUSG00000043556Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-192l18.9ENSDARG0000007787866
fbxl20 / F-box and leucine-rich repeat protein 20 / Q96IG2* / Q9CZV8* / F-box/LRR-repeat protein 20 *ENSDARG0000007556725
fbxl2 / F-box and leucine-rich repeat protein 2 / Q8BH16* / Q9UKC9* / F-box/LRR-repeat protein 2 *ENSDARG0000001213522
lrrc29 / leucine rich repeat containing 29 / Q8WV35*ENSDARG0000007642519
fbxl4 / F-box and leucine-rich repeat protein 4 / Q8BH70* / Q9UKA2* / F-box/LRR-repeat protein 4 *ENSDARG0000002694118
fbxl16 / F-box and leucine-rich repeat protein 16 / A2RT62* / Q8N461* / F-box/LRR-repeat protein 16 *ENSDARG0000006091518
fbxl14a / F-box and leucine-rich repeat protein 14a / Q8N1E6* / FBXL14* / Q8BID8* / F-box/LRR-repeat protein 14 * / F-box and leucine rich repeat protein 14*ENSDARG0000003449717
fbxl14b / F-box and leucine-rich repeat protein 14b / Q8N1E6* / FBXL14* / Q8BID8* / F-box/LRR-repeat protein 14 * / F-box and leucine rich repeat protein 14*ENSDARG0000004580116
fbxl13 / F-box and leucine-rich repeat protein 13 / Q8NEE6*ENSDARG0000007619116
fbxl15 / F-box and leucine-rich repeat protein 15 / Q91W61* / Q9H469* / F-box/LRR-repeat protein 15 *ENSDARG0000000528413
fbxl17 / F-box and leucine-rich repeat protein 17 / Q9QZN1* / Q9UF56* / F-box/LRR-repeat protein 17 *ENSDARG0000004207210


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001810  F-box domain
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA


Pathways (from Reactome)
Pathway description
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex / reaction
 ENSDARG00000003151 skp1 / S-phase kinase-associated protein 1 / Skp1a* / P63208* / Q9WTX5* / AC104109.3* / S-phase kinase-associated protein 1A*  / complex / reaction
 ENSDARG00000019239 cul1a / cullin 1a / CUL1* / Q13616* / Q9WTX6* / cullin 1* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*  / complex / reaction






 

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