ENSDARG00000062272


Danio rerio

Features
Gene ID: ENSDARG00000062272
  
Biological name :afg3l2
  
Synonyms : afg3l2 / AFG3-like AAA ATPase 2
  
Possible biological names infered from orthology : AFG3 like matrix AAA peptidase subunit 2 / AFG3-like protein 2 / Q8JZQ2 / Q9Y4W6
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 21452822
Gene end: 21469898
  
Corresponding Affymetrix probe sets: Dr.14054.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000138163
NCBI entrez gene - 569168     See in Manteia.
RefSeq - NM_001111197
RefSeq Peptide - NP_001104667
swissprot - A0A0R4IUQ8
swissprot - A9JRG9
ZFIN ID - ZDB-GENE-070912-46
Ensembl - ENSDARG00000062272
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AFG3L2ENSGALG00000013853Gallus gallus
 AFG3L2ENSG00000141385Homo sapiens
 Afg3l2ENSMUSG00000024527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch1073-174d20.2 / Afg3l1* / Q920A7* / AFG3-like protein 1 *ENSDARG0000007965166
spg7 / spastic paraplegia 7 / Q9UQ90* / Q3ULF4* / Paraplegin * / SPG7, paraplegin matrix AAA peptidase subunit*ENSDARG0000006818731


Protein motifs (from Interpro)
Interpro ID Name
 IPR000642  Peptidase M41
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR005936  Peptidase, FtsH
 IPR011546  Peptidase M41, FtsH extracellular
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000069671 maip1 / matrix AAA peptidase interacting protein 1 / Q8BHE8* / Q8WWC4* / m-AAA protease-interacting protein 1, mitochondrial *  / complex
 ENSDARG00000068187 spg7 / spastic paraplegia 7 / Q9UQ90* / Q3ULF4* / Paraplegin * / SPG7, paraplegin matrix AAA peptidase subunit*  / complex
 ENSDARG00000057414 phb / prohibitin / P35232* / P67778*  / complex
 ENSDARG00000045297 phb2a / prohibitin 2a / PHB2* / Q99623* / prohibitin 2*  / complex
 ENSDARG00000017728 phb2b / prohibitin 2b / PHB2* / O35129* / Q99623* / prohibitin 2*  / complex
 ENSDARG00000098852 smdt1b / single-pass membrane protein with aspartate-rich tail 1b / SMDT1* / Q9DB10* / Q9H4I9* / single-pass membrane protein with aspartate rich tail 1*  / reaction / complex






 

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