ENSGALG00000013853


Gallus gallus

Features
Gene ID: ENSGALG00000013853
  
Biological name :AFG3L2
  
Synonyms : AFG3L2 / AFG3 like matrix AAA peptidase subunit 2
  
Possible biological names infered from orthology : AFG3-like protein 2 / Q8JZQ2 / Q9Y4W6
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 97433438
Gene end: 97456386
  
Corresponding Affymetrix probe sets: Gga.4152.1.S1_s_at (Chicken Array)   GgaAffx.24294.1.S1_at (Chicken Array)   GgaAffx.24294.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000022434
Ensembl peptide - ENSGALP00000055622
NCBI entrez gene - 421036     See in Manteia.
RefSeq - XM_419121
RefSeq - XM_004939724
swissprot - E1BZ74
swissprot - A0A1D5PRU3
Ensembl - ENSGALG00000013853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 afg3l2ENSDARG00000062272Danio rerio
 AFG3L2ENSG00000141385Homo sapiens
 Afg3l2ENSMUSG00000024527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPG7 / paraplegin / Q3ULF4* / Q9UQ90* / SPG7, paraplegin matrix AAA peptidase subunit*ENSGALG0000002836332


Protein motifs (from Interpro)
Interpro ID Name
 IPR000642  Peptidase M41
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR005936  Peptidase, FtsH
 IPR011546  Peptidase M41, FtsH extracellular
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0008053 mitochondrial fusion IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0016540 protein autoprocessing IEA
 biological_processGO:0021675 nerve development IEA
 biological_processGO:0034982 mitochondrial protein processing IEA
 biological_processGO:0036444 calcium import into the mitochondrion IEA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0042407 cristae formation IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0048747 muscle fiber development IEA
 biological_processGO:0051560 mitochondrial calcium ion homeostasis IEA
 biological_processGO:0060013 righting reflex IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005745 m-AAA complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008280 PMPCB / peptidase, mitochondrial processing beta subunit / O75439* / Q9CXT8* / peptidase (mitochondrial processing) beta*  / reaction
 ENSGALG00000014567 PHB2 / prohibitin-2 / O35129* / Q99623*  / complex
 ENSGALG00000038604 PHB / P84173 / Prohibitin / P35232* / P67778*  / complex
 ENSGALG00000011897 SMDT1 / single-pass membrane protein with aspartate rich tail 1 / Q9DB10* / Q9H4I9*  / complex / reaction






 

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