ENSGALG00000014567


Gallus gallus

Features
Gene ID: ENSGALG00000014567
  
Biological name :PHB2
  
Synonyms : PHB2 / prohibitin-2
  
Possible biological names infered from orthology : O35129 / Q99623
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 77348875
Gene end: 77354569
  
Corresponding Affymetrix probe sets: GgaAffx.11454.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000060493
Ensembl peptide - ENSGALP00000062530
Ensembl peptide - ENSGALP00000023446
NCBI entrez gene - 771124     See in Manteia.
RefSeq - NM_001080885
RefSeq - XM_015293575
RefSeq Peptide - NP_001074354
swissprot - A0A1L1RNY5
swissprot - F1N833
Ensembl - ENSGALG00000014567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phb2aENSDARG00000045297Danio rerio
 phb2bENSDARG00000017728Danio rerio
 PHB2ENSG00000215021Homo sapiens
 Phb2ENSMUSG00000004264Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000163  Prohibitin
 IPR001107  Band 7 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007062 sister chromatid cohesion IEA
 biological_processGO:0031536 positive regulation of exit from mitosis IEA
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0033600 negative regulation of mammary gland epithelial cell proliferation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0060744 mammary gland branching involved in thelarche IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0060762 regulation of branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:1902808 positive regulation of cell cycle G1/S phase transition IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0033218 amide binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008280 PMPCB / peptidase, mitochondrial processing beta subunit / O75439* / Q9CXT8* / peptidase (mitochondrial processing) beta*  / reaction
 ENSGALG00000013853 AFG3L2 / AFG3 like matrix AAA peptidase subunit 2 / Q8JZQ2* / Q9Y4W6* / AFG3-like protein 2 *  / complex
 ENSGALG00000038604 PHB / P84173 / Prohibitin / P35232* / P67778*  / complex
 ENSGALG00000014567 PHB2 / prohibitin-2 / O35129* / Q99623*  / complex
 ENSGALG00000011897 SMDT1 / single-pass membrane protein with aspartate rich tail 1 / Q9DB10* / Q9H4I9*  / reaction / complex






 

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