ENSDARG00000063726


Danio rerio

Features
Gene ID: ENSDARG00000063726
  
Biological name :cdk12
  
Synonyms : cdk12 / cyclin-dependent kinase 12
  
Possible biological names infered from orthology : Q14AX6 / Q9NYV4
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 4856351
Gene end: 4905342
  
Corresponding Affymetrix probe sets: Dr.3033.2.A1_at (Zebrafish Array)   Dr.3033.2.A1_x_at (Zebrafish Array)   Dr.3033.3.A1_a_at (Zebrafish Array)   Dr.3033.3.A1_x_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000087834
Ensembl peptide - ENSDARP00000126079
Ensembl peptide - ENSDARP00000126170
NCBI entrez gene - 100149834     See in Manteia.
RefSeq - XM_003200531
swissprot - F1R6Y1
swissprot - I3IT26
swissprot - I3ITA7
ZFIN ID - ZDB-GENE-081104-294
Ensembl - ENSDARG00000063726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDK12ENSGALG00000001731Gallus gallus
 CDK12ENSG00000167258Homo sapiens
 Cdk12ENSMUSG00000003119Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdk13 / cyclin-dependent kinase 13 / Q14004* / Q69ZA1*ENSDARG0000007679135
cdk9 / cyclin-dependent kinase 9 (CDC2-related kinase) / P50750* / Q99J95* / cyclin dependent kinase 9*ENSDARG000000448119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0070816 phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0008024 cyclin/CDK positive transcription elongation factor complex IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IBA
 molecular_functionGO:0030332 cyclin binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of DNA Repair Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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