ENSDARG00000069945


Danio rerio

Features
Gene ID: ENSDARG00000069945
  
Biological name :p2ry12
  
Synonyms : p2ry12 / purinergic receptor P2Y12
  
Possible biological names infered from orthology : purinergic receptor P2Y, G-protein coupled 12 / Q9CPV9 / Q9H244
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 1116664
Gene end: 1120421
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128926
Ensembl peptide - ENSDARP00000093000
NCBI entrez gene - 100149618     See in Manteia.
RefSeq - NM_001308557
RefSeq Peptide - NP_001295486
swissprot - E7F2G6
ZFIN ID - ZDB-GENE-110208-4
Ensembl - ENSDARG00000069945
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RY12ENSGALG00000036470Gallus gallus
 P2RY12ENSG00000169313Homo sapiens
 P2ry12ENSMUSG00000036353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
p2ry13 / purinergic receptor P2Y13 / Q9BPV8* / Q9D8I2* / P2Y purinoceptor 13 *ENSDARG0000006994442
P2RY14 / purinergic receptor P2Y14 / Q15391*ENSDARG0000010330534
gpr34b / G protein-coupled receptor 34b / GPR34* / Q9R1K6* / Q9UPC5* / G protein-coupled receptor 34* / Probable G-protein coupled receptor 34 *ENSDARG0000000295926
si:ch73-309g22.1ENSDARG0000009949526
gpr171 / G protein-coupled receptor 171 / O14626*ENSDARG0000010500826
CR626884.1ENSDARG0000010059525
CR626884.4ENSDARG0000011612324
CR626884.5ENSDARG0000011710924
CR626884.3ENSDARG0000010464821
si:dkey-216e24.9 / GPR82* / Q8BZR0* / Q96P67* / G protein-coupled receptor 82* / Probable G-protein coupled receptor 82 *ENSDARG0000009341818


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR005394  P2Y12 purinoceptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation IMP
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA


Pathways (from Reactome)
Pathway description
ADP signalling through P2Y purinoceptor 12
P2Y receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / complex / reaction
 ENSDARG00000018174 gnai2a / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a / GNAI2* / P08752* / P04899* / G protein subunit alpha i2* / guanine nucleotide binding pro...  / reaction / complex
 ENSDARG00000030644 gnai3 / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 / GNAI1* / B2RSH2* / P08754* / P63096* / Q9DC51* / G protein subunit alpha i1* / G protein su...  / reaction / complex
 ENSDARG00000017294 gnai2b / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b / GNAI2* / P08752* / P04899* / G protein subunit alpha i2* / guanine nucleotide binding pro...  / complex / reaction
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / reaction / complex
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction






 

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