ENSDARG00000071336


Danio rerio

Features
Gene ID: ENSDARG00000071336
  
Biological name :mif
  
Synonyms : macrophage migration inhibitory factor / mif
  
Possible biological names infered from orthology : macrophage migration inhibitory factor (glycosylation-inhibiting factor) / P14174 / P34884
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 48960078
Gene end: 48970210
  
Corresponding Affymetrix probe sets: Dr.7856.1.S1_at (Zebrafish Array)   NM_001043321_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000096200
Ensembl peptide - ENSDARP00000136013
NCBI entrez gene - 751093     See in Manteia.
RefSeq - NM_001043321
RefSeq Peptide - NP_001036786
swissprot - Q0ZBR7
ZFIN ID - ZDB-GENE-080708-1
Ensembl - ENSDARG00000071336
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MIFENSGALG00000006326Gallus gallus
 MIFENSG00000240972Homo sapiens
 MifENSMUSG00000033307Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001398  Macrophage migration inhibitory factor
 IPR014347  Tautomerase/MIF superfamily
 IPR019829  Macrophage migration inhibitory factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0048598 embryonic morphogenesis IMP
 biological_processGO:0048839 inner ear development IGI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
brain apoptotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system attenuate , abnormal
Show

 ZFA:0000013 cranial ganglion cranial ganglion neuron projection decreased length , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
hindbrain apoptotic , abnormal
Show

 ZFA:0000030 macula utricle macula utricle has fewer parts of type hair cell , abnormal
Show

 ZFA:0000035 lens lens decreased size , abnormal
Show

 ZFA:0000107 eye eye attenuate , abnormal
eye decreased size , abnormal
eye malformed , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
Show

 ZFA:0000152 retina retina apoptotic , abnormal
retina shape , abnormal
Show

 ZFA:0000217 inner ear inner ear apoptotic , abnormal
inner ear attenuate , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal malformed , abnormal
Show

 ZFA:0000445 optic tectum optic tectum swollen , abnormal
optic tectum apoptotic , abnormal
Show

 ZFA:0000588 statoacoustic (VIII) ganglion statoacoustic (VIII) ganglion has fewer parts of type neuroblast , abnormal
statoacoustic (VIII) ganglion decreased size , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin malformed , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
Show

 ZFA:0001312 dorsal anterior lateral line ganglion dorsal anterior lateral line ganglion decreased size , abnormal
Show

 ZFA:0001326 lens epithelium lens epithelium vacuolated , abnormal
Show

 ZFA:0001717 pillar of the semicircular canal pillar of the semicircular canal unfused from pillar of the semicircular canal , abnormal
Show

 ZFA:0007000 macula saccule macula saccule has fewer parts of type hair cell , abnormal
Show

 ZFA:0009255 amacrine cell amacrine cell decreased amount , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell decreased amount , abnormal
Show

 ZFA:0009318 retinal bipolar neuron retinal bipolar neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / complex / reaction
 ENSDARG00000071336 mif / macrophage migration inhibitory factor / P14174* / P34884* / macrophage migration inhibitory factor (glycosylation-inhibiting factor)*  / complex






 

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