ENSDARG00000074064


Danio rerio

Features
Gene ID: ENSDARG00000074064
  
Biological name :rem2
  
Synonyms : RAS (RAD and GEM)-like GTP binding 2 / rem2
  
Possible biological names infered from orthology : Q8IYK8 / RRAD and GEM like GTPase 2
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 38924975
Gene end: 38977298
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000100974
NCBI entrez gene - 798285     See in Manteia.
RefSeq - NM_001123046
RefSeq Peptide - NP_001116518
swissprot - B0R168
ZFIN ID - ZDB-GENE-081110-1
Ensembl - ENSDARG00000074064
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 REM2ENSG00000139890Homo sapiens
 Rem2ENSMUSG00000022176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rrad / Ras-related associated with diabetes / P55042* / RRAD, Ras related glycolysis inhibitor and calcium channel regulator*ENSDARG0000005201135
rem1 / RAS (RAD and GEM)-like GTP-binding 1 / O75628* / O35929* / GTP-binding protein REM 1 * / RRAD and GEM like GTPase 1*ENSDARG0000002054433
gem / GTP binding protein overexpressed in skeletal muscle / P55040* / P55041* / GTP-binding protein GEM *ENSDARG0000002911231
A1DZY4 / rasl11a / RAS-like, family 11, member A / Q6T310* / Q6IMB1* / Ras-like protein family member 11A *ENSDARG0000004601319
ralaa / v-ral simian leukemia viral oncogene homolog Aa (ras related) / RALA* / P63321* / P11233* / RAS like proto-oncogene A* / Ras-related protein Ral-A *ENSDARG0000004546317
ralab / v-ral simian leukemia viral oncogene homolog Ab (ras related) / RALA* / P63321* / P11233* / RAS like proto-oncogene A* / Ras-related protein Ral-A *ENSDARG0000001625316
rras / RAS related / P10301* / P10833* / related RAS viral (r-ras) oncogene*ENSDARG0000000655316
rras2 / RAS related 2 / P62070* / P62071* / Ras-related protein R-Ras2 *ENSDARG0000003625216
Q6P0U3 / rasl11b / RAS-like, family 11, member B / Q9BPW5* / Q922H7* / Ras-like protein family member 11B *ENSDARG0000001561116
Q7SZ59 / rasl12 / RAS-like, family 12 / Q9NYN1*ENSDARG0000000270116
ralba / v-ral simian leukemia viral oncogene homolog Ba (ras related) / RALB* / Q9JIW9* / P11234* / RAS like proto-oncogene B* / Ras-related protein Ral-B *ENSDARG0000004077816
mras / muscle RAS oncogene homolog / O08989* / O14807* / muscle and microspikes RAS*ENSDARG0000006286516
MRAS / si:ch73-116o1.2 / O08989* / O14807* / muscle and microspikes RAS* / muscle RAS oncogene homolog*ENSDARG0000007528516
rergla / RERG/RAS-like a / RERGL* / Q9H628* / RERG like* / RERG/RAS-like*ENSDARG0000001939616
si:dkeyp-59c12.1ENSDARG0000003811215
hrasb / -Ha-ras Harvey rat sarcoma viral oncogene homolog b / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*ENSDARG0000000565115
rerglb / RERG/RAS-like bENSDARG0000005432415
zgc:64022ENSDARG0000007070514
zgc:55558ENSDARG0000001316114
kras / v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologENSDARG0000001084414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005246 calcium channel regulator activity IDA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system dopaminergic neuron apoptotic , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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