ENSG00000139890


Homo sapiens

Features
Gene ID: ENSG00000139890
  
Biological name :REM2
  
Synonyms : Q8IYK8 / REM2 / RRAD and GEM like GTPase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 22883165
Gene end: 22887686
  
Corresponding Affymetrix probe sets: 235699_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000267396
Ensembl peptide - ENSP00000442774
NCBI entrez gene - 161253     See in Manteia.
OMIM - 616955
RefSeq - XM_017021059
RefSeq - NM_173527
RefSeq - XM_005267383
RefSeq - XM_017021058
RefSeq Peptide - NP_775798
swissprot - Q8IYK8
Ensembl - ENSG00000139890
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rem2ENSDARG00000074064Danio rerio
 Rem2ENSMUSG00000022176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAD / P55042 / RRAD, Ras related glycolysis inhibitor and calcium channel regulatorENSG0000016659244
GEM / P55040 / GTP binding protein overexpressed in skeletal muscleENSG0000016494938
REM1 / O75628 / RRAD and GEM like GTPase 1ENSG0000008832036
RALA / P11233 / RAS like proto-oncogene AENSG0000000645119
RRAS / P10301 / RAS relatedENSG0000012645818
RRAS2 / P62070 / RAS related 2ENSG0000013381818
MRAS / O14807 / muscle RAS oncogene homologENSG0000015818618
Q9NYN1 / RASL12 / RAS like family 12ENSG0000010371018
RALB / P11234 / RAS like proto-oncogene BENSG0000014411818
Q6T310 / RASL11A / RAS like family 11 member AENSG0000012203517
Q9BPW5 / RASL11B / RAS like family 11 member BENSG0000012804517
NRAS / P01111 / NRAS proto-oncogene, GTPaseENSG0000021328116
RERG / Q96A58 / RAS like estrogen regulated growth inhibitorENSG0000013453316
KRAS / P01116 / KRAS proto-oncogene, GTPaseENSG0000013370316
ERAS / Q7Z444 / ES cell expressed RasENSG0000018768215
HRAS / P01112 / HRas proto-oncogene, GTPaseENSG0000017477515
RERGL / Q9H628 / RERG likeENSG0000011140414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR017358  Ras-related small G protein, RGK family
 IPR020849  Small GTPase superfamily, Ras-type
 IPR025662  Sigma-54 interaction domain, ATP-binding site 1
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:1901842 negative regulation of high voltage-gated calcium channel activity IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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