ENSG00000133818


Homo sapiens

Features
Gene ID: ENSG00000133818
  
Biological name :RRAS2
  
Synonyms : P62070 / RAS related 2 / RRAS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.2
Gene start: 14277926
Gene end: 14364506
  
Corresponding Affymetrix probe sets: 208456_s_at (Human Genome U133 Plus 2.0 Array)   212589_at (Human Genome U133 Plus 2.0 Array)   212590_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434104
Ensembl peptide - ENSP00000437547
Ensembl peptide - ENSP00000437083
Ensembl peptide - ENSP00000436887
Ensembl peptide - ENSP00000436190
Ensembl peptide - ENSP00000435453
Ensembl peptide - ENSP00000256196
Ensembl peptide - ENSP00000403282
Ensembl peptide - ENSP00000431954
Ensembl peptide - ENSP00000432559
Ensembl peptide - ENSP00000433230
NCBI entrez gene - 22800     See in Manteia.
OMIM - 600098
RefSeq - XM_017017363
RefSeq - NM_001102669
RefSeq - NM_001177314
RefSeq - NM_001177315
RefSeq - NM_012250
RefSeq Peptide - NP_001170786
RefSeq Peptide - NP_001096139
RefSeq Peptide - NP_001170785
RefSeq Peptide - NP_036382
swissprot - E9PQC5
swissprot - E9PQ87
swissprot - P62070
swissprot - E9PQK5
swissprot - E9PK85
Ensembl - ENSG00000133818
  
Related genetic diseases (OMIM): 600098 - Ovarian carcinoma
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rras2ENSDARG00000036252Danio rerio
 RRAS2ENSGALG00000005998Gallus gallus
 Rras2ENSMUSG00000055723Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAS / P10301 / RAS relatedENSG0000012645865
MRAS / O14807 / muscle RAS oncogene homologENSG0000015818656
HRAS / P01112 / HRas proto-oncogene, GTPaseENSG0000017477551
KRAS / P01116 / KRAS proto-oncogene, GTPaseENSG0000013370350
NRAS / P01111 / NRAS proto-oncogene, GTPaseENSG0000021328149
RALA / P11233 / RAS like proto-oncogene AENSG0000000645147
RALB / P11234 / RAS like proto-oncogene BENSG0000014411846
RERG / Q96A58 / RAS like estrogen regulated growth inhibitorENSG0000013453339
ERAS / Q7Z444 / ES cell expressed RasENSG0000018768236
REM1 / O75628 / RRAD and GEM like GTPase 1ENSG0000008832031
RRAD / P55042 / RRAD, Ras related glycolysis inhibitor and calcium channel regulatorENSG0000016659230
REM2 / Q8IYK8 / RRAD and GEM like GTPase 2ENSG0000013989030
GEM / P55040 / GTP binding protein overexpressed in skeletal muscleENSG0000016494930
Q9NYN1 / RASL12 / RAS like family 12ENSG0000010371029
Q6T310 / RASL11A / RAS like family 11 member AENSG0000012203529
Q9BPW5 / RASL11B / RAS like family 11 member BENSG0000012804526
RERGL / Q9H628 / RERG likeENSG0000011140423


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007265 Ras protein signal transduction IEA
 biological_processGO:0009987 cellular process IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:1901214 regulation of neuron death IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum NAS
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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