ENSG00000088320


Homo sapiens

Features
Gene ID: ENSG00000088320
  
Biological name :REM1
  
Synonyms : O75628 / REM1 / RRAD and GEM like GTPase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.21
Gene start: 31475293
Gene end: 31484905
  
Corresponding Affymetrix probe sets: 210300_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000201979
NCBI entrez gene - 28954     See in Manteia.
OMIM - 610388
RefSeq - XM_017027833
RefSeq - NM_014012
RefSeq - XM_005260404
RefSeq - XM_011528795
RefSeq Peptide - NP_054731
swissprot - O75628
Ensembl - ENSG00000088320
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rem1ENSDARG00000020544Danio rerio
 REM1ENSGALG00000045602Gallus gallus
 Rem1ENSMUSG00000000359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAD / P55042 / RRAD, Ras related glycolysis inhibitor and calcium channel regulatorENSG0000016659251
GEM / P55040 / GTP binding protein overexpressed in skeletal muscleENSG0000016494950
REM2 / Q8IYK8 / RRAD and GEM like GTPase 2ENSG0000013989041
RRAS / P10301 / RAS relatedENSG0000012645822
RERG / Q96A58 / RAS like estrogen regulated growth inhibitorENSG0000013453321
RRAS2 / P62070 / RAS related 2ENSG0000013381821
RALA / P11233 / RAS like proto-oncogene AENSG0000000645120
Q9BPW5 / RASL11B / RAS like family 11 member BENSG0000012804520
ERAS / Q7Z444 / ES cell expressed RasENSG0000018768219
RALB / P11234 / RAS like proto-oncogene BENSG0000014411819
Q9NYN1 / RASL12 / RAS like family 12ENSG0000010371019
MRAS / O14807 / muscle RAS oncogene homologENSG0000015818619
Q6T310 / RASL11A / RAS like family 11 member AENSG0000012203518
KRAS / P01116 / KRAS proto-oncogene, GTPaseENSG0000013370318
NRAS / P01111 / NRAS proto-oncogene, GTPaseENSG0000021328118
HRAS / P01112 / HRas proto-oncogene, GTPaseENSG0000017477518
RERGL / Q9H628 / RERG likeENSG0000011140417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR017358  Ras-related small G protein, RGK family
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:1901842 negative regulation of high voltage-gated calcium channel activity IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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