ENSG00000134533


Homo sapiens

Features
Gene ID: ENSG00000134533
  
Biological name :RERG
  
Synonyms : Q96A58 / RAS like estrogen regulated growth inhibitor / RERG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p12.3
Gene start: 15107783
Gene end: 15348675
  
Corresponding Affymetrix probe sets: 227758_at (Human Genome U133 Plus 2.0 Array)   244745_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000441505
Ensembl peptide - ENSP00000441860
Ensembl peptide - ENSP00000444485
Ensembl peptide - ENSP00000256953
Ensembl peptide - ENSP00000438280
Ensembl peptide - ENSP00000439532
Ensembl peptide - ENSP00000440887
NCBI entrez gene - 85004     See in Manteia.
OMIM - 612664
RefSeq - XM_017020121
RefSeq - NM_001190726
RefSeq - NM_032918
RefSeq Peptide - NP_001177655
RefSeq Peptide - NP_116307
swissprot - A0A024RAT4
swissprot - F5H252
swissprot - F5GYR1
swissprot - F5GWE9
swissprot - Q96A58
Ensembl - ENSG00000134533
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RERGENSDARG00000104632Danio rerio
 RERGENSGALG00000028186Gallus gallus
 RergENSMUSG00000030222Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAS2 / P62070 / RAS related 2ENSG0000013381840
Q6T310 / RASL11A / RAS like family 11 member AENSG0000012203537
Q9NYN1 / RASL12 / RAS like family 12ENSG0000010371036
MRAS / O14807 / muscle RAS oncogene homologENSG0000015818635
RRAS / P10301 / RAS relatedENSG0000012645835
KRAS / P01116 / KRAS proto-oncogene, GTPaseENSG0000013370335
NRAS / P01111 / NRAS proto-oncogene, GTPaseENSG0000021328134
RALA / P11233 / RAS like proto-oncogene AENSG0000000645134
HRAS / P01112 / HRas proto-oncogene, GTPaseENSG0000017477534
Q9BPW5 / RASL11B / RAS like family 11 member BENSG0000012804533
RERGL / Q9H628 / RERG likeENSG0000011140432
RALB / P11234 / RAS like proto-oncogene BENSG0000014411832
REM1 / O75628 / RRAD and GEM like GTPase 1ENSG0000008832031
RRAD / P55042 / RRAD, Ras related glycolysis inhibitor and calcium channel regulatorENSG0000016659229
GEM / P55040 / GTP binding protein overexpressed in skeletal muscleENSG0000016494929
REM2 / Q8IYK8 / RRAD and GEM like GTPase 2ENSG0000013989028
ERAS / Q7Z444 / ES cell expressed RasENSG0000018768224


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction NAS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009725 response to hormone IDA
 biological_processGO:0030308 negative regulation of cell growth IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding TAS
 molecular_functionGO:0030331 estrogen receptor binding NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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