ENSG00000158186


Homo sapiens

Features
Gene ID: ENSG00000158186
  
Biological name :MRAS
  
Synonyms : MRAS / muscle RAS oncogene homolog / O14807
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q22.3
Gene start: 138347648
Gene end: 138405534
  
Corresponding Affymetrix probe sets: 206538_at (Human Genome U133 Plus 2.0 Array)   225185_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419582
Ensembl peptide - ENSP00000418356
Ensembl peptide - ENSP00000481637
Ensembl peptide - ENSP00000484586
Ensembl peptide - ENSP00000289104
Ensembl peptide - ENSP00000389682
Ensembl peptide - ENSP00000417092
Ensembl peptide - ENSP00000417685
NCBI entrez gene - 22808     See in Manteia.
OMIM - 608435
RefSeq - XM_017005887
RefSeq - NM_001085049
RefSeq - NM_001252090
RefSeq - NM_001252091
RefSeq - NM_001252092
RefSeq - NM_001252093
RefSeq - NM_012219
RefSeq - XM_005247228
RefSeq - XM_005247229
RefSeq Peptide - NP_001078518
RefSeq Peptide - NP_001239020
RefSeq Peptide - NP_001239021
RefSeq Peptide - NP_001239022
RefSeq Peptide - NP_036351
RefSeq Peptide - NP_001239019
swissprot - C9J8Q6
swissprot - O14807
swissprot - Q6FGP0
swissprot - C9J601
Ensembl - ENSG00000158186
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mrasENSDARG00000062865Danio rerio
 MRASENSDARG00000075285Danio rerio
 MRASENSGALG00000011592Gallus gallus
 MrasENSMUSG00000032470Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAS2 / P62070 / RAS related 2ENSG0000013381855
RRAS / P10301 / RAS relatedENSG0000012645849
KRAS / P01116 / KRAS proto-oncogene, GTPaseENSG0000013370348
NRAS / P01111 / NRAS proto-oncogene, GTPaseENSG0000021328148
HRAS / P01112 / HRas proto-oncogene, GTPaseENSG0000017477547
RALA / P11233 / RAS like proto-oncogene AENSG0000000645143
RALB / P11234 / RAS like proto-oncogene BENSG0000014411841
ERAS / Q7Z444 / ES cell expressed RasENSG0000018768234
RERG / Q96A58 / RAS like estrogen regulated growth inhibitorENSG0000013453333
RRAD / P55042 / RRAD, Ras related glycolysis inhibitor and calcium channel regulatorENSG0000016659231
REM2 / Q8IYK8 / RRAD and GEM like GTPase 2ENSG0000013989030
GEM / P55040 / GTP binding protein overexpressed in skeletal muscleENSG0000016494929
Q9NYN1 / RASL12 / RAS like family 12ENSG0000010371028
REM1 / O75628 / RRAD and GEM like GTPase 1ENSG0000008832028
Q9BPW5 / RASL11B / RAS like family 11 member BENSG0000012804526
Q6T310 / RASL11A / RAS like family 11 member AENSG0000012203525
RERGL / Q9H628 / RERG likeENSG0000011140423


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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