ENSMUSG00000032470


Mus musculus

Features
Gene ID: ENSMUSG00000032470
  
Biological name :Mras
  
Synonyms : Mras / muscle and microspikes RAS / O08989
  
Possible biological names infered from orthology : muscle RAS oncogene homolog / O14807
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.3
Gene start: 99385420
Gene end: 99437381
  
Corresponding Affymetrix probe sets: 10595979 (MoGene1.0st)   10595981 (MoGene1.0st)   1449590_a_at (Mouse Genome 430 2.0 Array)   1453419_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121307
Ensembl peptide - ENSMUSP00000035045
Ensembl peptide - ENSMUSP00000112407
Ensembl peptide - ENSMUSP00000113275
NCBI entrez gene - 17532     See in Manteia.
MGI - MGI:1100856
RefSeq - NM_008624
RefSeq - XM_006510825
RefSeq Peptide - NP_032650
swissprot - D3Z2V6
swissprot - O08989
swissprot - Q3TPX5
Ensembl - ENSMUSG00000032470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mrasENSDARG00000062865Danio rerio
 MRASENSDARG00000075285Danio rerio
 MRASENSGALG00000011592Gallus gallus
 MRASENSG00000158186Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rras2 / P62071 / Ras-related protein R-Ras2 / P62070* / RAS related 2*ENSMUSG0000005572355
Rras / P10833 / related RAS viral (r-ras) oncogene / P10301* / RAS related*ENSMUSG0000003838749
Nras / neuroblastoma ras oncogene / P01111* / NRAS proto-oncogene, GTPase*ENSMUSG0000002785248
Hras / Q61411 / GTPase HRas GTPase HRas, N-terminally processed / P01112* / HRas proto-oncogene, GTPase*ENSMUSG0000002549948
Kras / P32883 / GTPase KRas GTPase KRas, N-terminally processed / P01116* / KRAS proto-oncogene, GTPase*ENSMUSG0000003026547
Rala / P63321 / Ras-related protein Ral-A / P11233* / RAS like proto-oncogene A*ENSMUSG0000000885943
Ralb / Q9JIW9 / Ras-related protein Ral-B / P11234* / RAS like proto-oncogene B*ENSMUSG0000000445142
Eras / Q7TN89 / GTPase ERas / Q7Z444* / ES cell expressed Ras*ENSMUSG0000003116038
Rerg / Q8R367 / Ras-related and estrogen-regulated growth inhibitor / Q96A58* / RAS like estrogen regulated growth inhibitor*ENSMUSG0000003022233
Rrad / Ras-related associated with diabetes / P55042* / RRAD, Ras related glycolysis inhibitor and calcium channel regulator*ENSMUSG0000003188031
Q08AT1 / Rasl12 / Ras-like protein family member 12 / Q9NYN1* / RAS like family 12*ENSMUSG0000004169630
Gem / P55041 / GTP-binding protein GEM / P55040* / GTP binding protein overexpressed in skeletal muscle*ENSMUSG0000002821429
Rem2 / RRAD and GEM like GTPase 2 / Q8IYK8*ENSMUSG0000002217629
Rem1 / O35929 / GTP-binding protein REM 1 / O75628* / RRAD and GEM like GTPase 1*ENSMUSG0000000035928
Rergl / RERG/RAS-like / Q9H628* / RERG like*ENSMUSG0000009216426
Q6IMB1 / Rasl11a / Ras-like protein family member 11A / Q6T310* / RAS like family 11 member A*ENSMUSG0000002964125
Q922H7 / Rasl11b / Ras-like protein family member 11B / Q9BPW5* / RAS like family 11 member B*ENSMUSG0000004990725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Sprntm1Geno/Sprntm1Geno
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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