ENSMUSG00000022176


Mus musculus

Features
Gene ID: ENSMUSG00000022176
  
Biological name :Rem2
  
Synonyms : Rem2 / RRAD and GEM like GTPase 2
  
Possible biological names infered from orthology : Q8IYK8
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C2
Gene start: 54476100
Gene end: 54480431
  
Corresponding Affymetrix probe sets: 10415074 (MoGene1.0st)   1448860_at (Mouse Genome 430 2.0 Array)   1457651_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127199
Ensembl peptide - ENSMUSP00000132998
Ensembl peptide - ENSMUSP00000131989
NCBI entrez gene - 140743     See in Manteia.
MGI - MGI:2155260
RefSeq - NM_080726
RefSeq Peptide - NP_542764
swissprot - E9Q4D5
swissprot - E9PVZ0
swissprot - F6Z0Z5
Ensembl - ENSMUSG00000022176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rem2ENSDARG00000074064Danio rerio
 REM2ENSG00000139890Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rrad / Ras-related associated with diabetes / P55042* / RRAD, Ras related glycolysis inhibitor and calcium channel regulator*ENSMUSG0000003188044
Gem / P55041 / GTP-binding protein GEM / P55040* / GTP binding protein overexpressed in skeletal muscle*ENSMUSG0000002821438
Rem1 / O35929 / GTP-binding protein REM 1 / O75628* / RRAD and GEM like GTPase 1*ENSMUSG0000000035935
Mras / O08989 / muscle and microspikes RAS / O14807* / muscle RAS oncogene homolog*ENSMUSG0000003247018
Rras / P10833 / related RAS viral (r-ras) oncogene / P10301* / RAS related*ENSMUSG0000003838718
Rala / P63321 / Ras-related protein Ral-A / P11233* / RAS like proto-oncogene A*ENSMUSG0000000885918
Rras2 / P62071 / Ras-related protein R-Ras2 / P62070* / RAS related 2*ENSMUSG0000005572318
Ralb / Q9JIW9 / Ras-related protein Ral-B / P11234* / RAS like proto-oncogene B*ENSMUSG0000000445117
Q08AT1 / Rasl12 / Ras-like protein family member 12 / Q9NYN1* / RAS like family 12*ENSMUSG0000004169617
Q922H7 / Rasl11b / Ras-like protein family member 11B / Q9BPW5* / RAS like family 11 member B*ENSMUSG0000004990717
Rergl / RERG/RAS-like / Q9H628* / RERG like*ENSMUSG0000009216416
Eras / Q7TN89 / GTPase ERas / Q7Z444* / ES cell expressed Ras*ENSMUSG0000003116016
Q6IMB1 / Rasl11a / Ras-like protein family member 11A / Q6T310* / RAS like family 11 member A*ENSMUSG0000002964116
Rerg / Q8R367 / Ras-related and estrogen-regulated growth inhibitor / Q96A58* / RAS like estrogen regulated growth inhibitor*ENSMUSG0000003022216
Kras / P32883 / GTPase KRas GTPase KRas, N-terminally processed / P01116* / KRAS proto-oncogene, GTPase*ENSMUSG0000003026515
Hras / Q61411 / GTPase HRas GTPase HRas, N-terminally processed / P01112* / HRas proto-oncogene, GTPase*ENSMUSG0000002549915
Nras / neuroblastoma ras oncogene / P01111* / NRAS proto-oncogene, GTPase*ENSMUSG0000002785215


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR017358  Ras-related small G protein, RGK family
 IPR020849  Small GTPase superfamily, Ras-type
 IPR025662  Sigma-54 interaction domain, ATP-binding site 1
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:1901842 negative regulation of high voltage-gated calcium channel activity IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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