ENSDARG00000074262


Danio rerio

Features
Gene ID: ENSDARG00000074262
  
Biological name :nck1a
  
Synonyms : nck1a / NCK adaptor protein 1a
  
Possible biological names infered from orthology : Cytoplasmic protein NCK1 / NCK1 / NCK adaptor protein 1 / P16333 / Q99M51
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 24963861
Gene end: 24981356
  
Corresponding Affymetrix probe sets: Dr.4260.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000102138
NCBI entrez gene - 564584     See in Manteia.
RefSeq - XM_687914
swissprot - E9QC52
ZFIN ID - ZDB-GENE-070912-547
Ensembl - ENSDARG00000074262
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NCK1ENSG00000158092Homo sapiens
 Nck1ENSMUSG00000032475Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nck1b / NCK adaptor protein 1b / NCK1* / P16333* / Q99M51* / NCK adaptor protein 1* / Cytoplasmic protein NCK1 *ENSDARG0000007536965
nck2a / NCK adaptor protein 2a / NCK2* / O43639* / O55033* / NCK adaptor protein 2* / Cytoplasmic protein NCK2 *ENSDARG0000001820656
nck2b / NCK adaptor protein 2b / NCK2* / O43639* / O55033* / NCK adaptor protein 2* / Cytoplasmic protein NCK2 *ENSDARG0000004336156
grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*ENSDARG0000010527617
grap2a / GRB2-related adaptor protein 2a / GRAP2* / O89100* / O75791* / GRB2-related adaptor protein 2*ENSDARG0000000646817
grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*ENSDARG0000003805916
grapb / GRB2-related adaptor protein b / GRAP* / GRAPL* / Q9CX99* / Q13588* / Q8TC17* / GRB2-related adaptor protein* / GRB2-related adapter protein * / GRB2 related adaptor protein like*ENSDARG0000002266816
grapa / GRB2-related adaptor protein a / GRAP* / GRAPL* / Q9CX99* / Q13588* / Q8TC17* / GRB2-related adaptor protein* / GRB2-related adapter protein * / GRB2 related adaptor protein like*ENSDARG0000000541415
grap2b / GRB2-related adaptor protein 2b / GRAP2* / O89100* / O75791* / GRB2-related adaptor protein 2*ENSDARG0000010116914


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001452  SH3 domain
 IPR017304  Cytoplasmic protein NCK
 IPR035564  Nck1, SH3 domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
Downstream signal transduction
Generation of second messenger molecules
Regulation of actin dynamics for phagocytic cup formation
Nephrin family interactions
DCC mediated attractive signaling
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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