ENSDARG00000022668


Danio rerio

Features
Gene ID: ENSDARG00000022668
  
Biological name :grapb
  
Synonyms : grapb / GRB2-related adaptor protein b
  
Possible biological names infered from orthology : GRAP / GRAPL / GRB2-related adapter protein / GRB2-related adaptor protein / GRB2 related adaptor protein like / Q13588 / Q8TC17 / Q9CX99
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 8165340
Gene end: 8192418
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000122058
NCBI entrez gene - 555184     See in Manteia.
RefSeq - NM_001030080
RefSeq Peptide - NP_001025251
swissprot - F1QSQ4
ZFIN ID - ZDB-GENE-050913-4
Ensembl - ENSDARG00000022668
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRAPENSGALG00000005094Gallus gallus
 GRAPENSG00000154016Homo sapiens
 GRAPLENSG00000189152Homo sapiens
 GrapENSMUSG00000004837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grapa / GRB2-related adaptor protein a / GRAP* / GRAPL* / Q9CX99* / Q13588* / Q8TC17* / GRB2-related adaptor protein* / GRB2-related adapter protein * / GRB2 related adaptor protein like*ENSDARG0000000541474
grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*ENSDARG0000010527652
grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*ENSDARG0000003805952
grap2a / GRB2-related adaptor protein 2a / GRAP2* / O89100* / O75791* / GRB2-related adaptor protein 2*ENSDARG0000000646849
grap2b / GRB2-related adaptor protein 2b / GRAP2* / O89100* / O75791* / GRB2-related adaptor protein 2*ENSDARG0000010116945
nck2a / NCK adaptor protein 2a / NCK2* / O43639* / O55033* / NCK adaptor protein 2* / Cytoplasmic protein NCK2 *ENSDARG0000001820626
nck1b / NCK adaptor protein 1b / NCK1* / P16333* / Q99M51* / NCK adaptor protein 1* / Cytoplasmic protein NCK1 *ENSDARG0000007536925
nck2b / NCK adaptor protein 2b / NCK2* / O43639* / O55033* / NCK adaptor protein 2* / Cytoplasmic protein NCK2 *ENSDARG0000004336125
nck1a / NCK adaptor protein 1a / NCK1* / P16333* / Q99M51* / NCK adaptor protein 1* / Cytoplasmic protein NCK1 *ENSDARG0000007426224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001452  SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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