ENSGALG00000005094


Gallus gallus

Features
Gene ID: ENSGALG00000005094
  
Biological name :GRAP
  
Synonyms : GRAP / GRB2-related adapter protein
  
Possible biological names infered from orthology : GRAPL / GRB2-related adaptor protein / GRB2 related adaptor protein like / Q13588 / Q8TC17 / Q9CX99
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 5192894
Gene end: 5196760
  
Corresponding Affymetrix probe sets: Gga.10880.1.S1_at (Chicken Array)   GgaAffx.3188.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000033231
NCBI entrez gene - 416523     See in Manteia.
RefSeq - NM_001277553
RefSeq Peptide - NP_001264482
swissprot - E1BXR0
Ensembl - ENSGALG00000005094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grapaENSDARG00000005414Danio rerio
 grapbENSDARG00000022668Danio rerio
 GRAPENSG00000154016Homo sapiens
 GRAPLENSG00000189152Homo sapiens
 GrapENSMUSG00000004837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*ENSGALG0000000801661
NCK2 / cytoplasmic protein NCK2 / O43639* / O55033* / NCK adaptor protein 2*ENSGALG0000001679923
GRAP2* / O75791* / O89100* / GRB2-related adaptor protein 2*ENSGALG0000001205613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001452  SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IBA


Pathways (from Reactome)
Pathway description
Signaling by SCF-KIT


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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