ENSGALG00000016799


Gallus gallus

Features
Gene ID: ENSGALG00000016799
  
Biological name :NCK2
  
Synonyms : cytoplasmic protein NCK2 / NCK2
  
Possible biological names infered from orthology : NCK adaptor protein 2 / O43639 / O55033
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 135367141
Gene end: 135448935
  
Corresponding Affymetrix probe sets: Gga.9033.1.S1_at (Chicken Array)   GgaAffx.12339.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027070
NCBI entrez gene - 418727     See in Manteia.
RefSeq - NM_001030814
RefSeq Peptide - NP_001025985
swissprot - F1P4Q4
Ensembl - ENSGALG00000016799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nck2aENSDARG00000018206Danio rerio
 nck2bENSDARG00000043361Danio rerio
 NCK2ENSG00000071051Homo sapiens
 Nck2ENSMUSG00000066877Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRAP / GRB2-related adapter protein / GRAPL* / Q9CX99* / Q13588* / Q8TC17* / GRB2-related adaptor protein* / GRB2 related adaptor protein like*ENSGALG0000000509413
GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*ENSGALG0000000801613
GRAP2* / O75791* / O89100* / GRB2-related adaptor protein 2*ENSGALG000000120561


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001452  SH3 domain
 IPR017304  Cytoplasmic protein NCK


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0036493 positive regulation of translation in response to endoplasmic reticulum stress IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903898 negative regulation of PERK-mediated unfolded protein response IEA
 biological_processGO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IEA
 biological_processGO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0012506 vesicle membrane IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IEA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
Downstream signal transduction
Nephrin family interactions
Ephrin signaling
VEGFA-VEGFR2 Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr