ENSGALG00000012056


Gallus gallus

Features
Gene ID: ENSGALG00000012056
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : GRAP2 / GRB2-related adaptor protein 2 / O75791 / O89100
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 50333673
Gene end: 50345718
  
Corresponding Affymetrix probe sets: GgaAffx.7644.1.S1_at (Chicken Array)   GgaAffx.7644.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019667
NCBI entrez gene - 770756     See in Manteia.
RefSeq - XM_001234081
RefSeq - XM_004937732
swissprot - E1BQF3
Ensembl - ENSGALG00000012056
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grap2aENSDARG00000006468Danio rerio
 grap2bENSDARG00000101169Danio rerio
 GRAP2ENSG00000100351Homo sapiens
 Grap2ENSMUSG00000042351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*ENSGALG0000000801628
GRAP / GRB2-related adapter protein / GRAPL* / Q9CX99* / Q13588* / Q8TC17* / GRB2-related adaptor protein* / GRB2 related adaptor protein like*ENSGALG0000000509421
NCK2 / cytoplasmic protein NCK2 / O43639* / O55033* / NCK adaptor protein 2*ENSGALG000000167994


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IBA


Pathways (from Reactome)
Pathway description
Signaling by SCF-KIT
Generation of second messenger molecules
DAP12 signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
CD28 co-stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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