ENSG00000189152


Homo sapiens

Features
Gene ID: ENSG00000189152
  
Biological name :GRAPL
  
Synonyms : GRAPL / GRB2 related adaptor protein like / Q8TC17
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p11.2
Gene start: 19127469
Gene end: 19159176
  
Corresponding Affymetrix probe sets: 1560524_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437409
Ensembl peptide - ENSP00000459618
Ensembl peptide - ENSP00000464934
Ensembl peptide - ENSP00000465788
Ensembl peptide - ENSP00000466091
NCBI entrez gene - 400581     See in Manteia.
RefSeq - XM_017024637
RefSeq - NM_001129778
RefSeq - NM_001353418
RefSeq - XM_011523857
RefSeq - XM_017024635
RefSeq - XM_017024636
RefSeq Peptide - NP_001123250
RefSeq Peptide - NP_001340347
swissprot - K7EIX7
swissprot - K7EKU7
swissprot - K7ELI1
swissprot - Q8TC17
swissprot - I3L2E9
Ensembl - ENSG00000189152
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grapaENSDARG00000005414Danio rerio
 grapbENSDARG00000022668Danio rerio
 GRAPENSGALG00000005094Gallus gallus
 GrapENSMUSG00000004837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRAP / Q13588 / GRB2-related adaptor proteinENSG0000015401692
GRB2 / P62993 / growth factor receptor bound protein 2ENSG0000017788561
GRAP2 / O75791 / GRB2-related adaptor protein 2ENSG0000010035143
NCK1 / P16333 / NCK adaptor protein 1ENSG0000015809236
NCK2 / O43639 / NCK adaptor protein 2ENSG0000007105134


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001452  SH3 domain
 IPR035645  GRAP, N-terminal SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr