ENSDARG00000074746


Danio rerio

Features
Gene ID: ENSDARG00000074746
  
Biological name :kcnd1
  
Synonyms : kcnd1 / potassium voltage-gated channel, Shal-related subfamily, member 1
  
Possible biological names infered from orthology : potassium voltage-gated channel subfamily D member 1 / Q03719 / Q9NSA2
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 9866351
Gene end: 9986978
  
Corresponding Affymetrix probe sets: Dr.11088.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000145124
Ensembl peptide - ENSDARP00000120299
NCBI entrez gene - 100001681     See in Manteia.
RefSeq - NM_001126470
RefSeq Peptide - NP_001119942
swissprot - B0UYF4
ZFIN ID - ZDB-GENE-081105-40
Ensembl - ENSDARG00000074746
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCND1ENSG00000102057Homo sapiens
 Kcnd1ENSMUSG00000009731Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kcnd3 / potassium voltage-gated channel, Shal-related subfamily, member 3 / Q9UK17* / Q9Z0V1* / potassium voltage-gated channel subfamily D member 3* / potassium voltage-gated channel, Shal...ENSDARG0000005610168
kcnd2 / potassium voltage-gated channel, Shal-related subfamily, member 2 / Q9NZV8* / Q9Z0V2* / potassium voltage-gated channel subfamily D member 2*ENSDARG0000003279967
kcna2a / potassium voltage-gated channel, shaker-related subfamily, member 2a / KCNA2* / P16389* / potassium voltage-gated channel subfamily A member 2*ENSDARG0000000224127
kcna2b / potassium voltage-gated channel, shaker-related subfamily, member 2b / KCNA2* / P16389* / potassium voltage-gated channel subfamily A member 2*ENSDARG0000010206427
kcna6a / potassium voltage-gated channel, shaker-related, subfamily, member 6 a / KCNA7* / Q17ST2* / Q96RP8* / potassium voltage-gated channel subfamily A member 7*ENSDARG0000004601427
kcna1a / potassium voltage-gated channel, shaker-related subfamily, member 1a / KCNA1* / P16388* / Q09470* / potassium voltage-gated channel subfamily A member 1*ENSDARG0000006294227
kcnc1a / potassium voltage-gated channel, Shaw-related subfamily, member 1a / KCNC1* / P15388* / P48547* / potassium voltage-gated channel subfamily C member 1*ENSDARG0000005185226
kcna1b / potassium voltage-gated channel, shaker-related subfamily, member 1b / KCNA1* / Q09470* / potassium voltage-gated channel subfamily A member 1*ENSDARG0000001710826
kcna4 / potassium voltage-gated channel, shaker-related subfamily, member 4 / P22459* / Q61423* / potassium voltage-gated channel subfamily A member 4*ENSDARG0000007865026
kcnc3b / potassium voltage-gated channel, Shaw-related subfamily, member 3b / KCNC3* / Q14003* / potassium voltage-gated channel subfamily C member 3* / potassium voltage-gated channel subf...ENSDARG0000009881626
kcnc4 / potassium voltage-gated channel, Shaw-related subfamily, member 4 / Q03721* / Q8R1C0* / potassium voltage-gated channel subfamily C member 4*ENSDARG0000006128825
kcnc1b / potassium voltage-gated channel, Shaw-related subfamily, member 1b / KCNC1* / P15388* / P48547* / potassium voltage-gated channel subfamily C member 1*ENSDARG0000003295925
kcnc3a / potassium voltage-gated channel, Shaw-related subfamily, member 3a / KCNC3* / Q14003* / potassium voltage-gated channel subfamily C member 3* / potassium voltage-gated channel subf...ENSDARG0000005585525
si:ch73-334d15.4ENSDARG0000005650217
kcnc2 / potassium voltage-gated channel, Shaw-related subfamily, member 2 / Q14B80* / Q96PR1* / potassium voltage-gated channel subfamily C member 2*ENSDARG0000005746816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003975  Potassium channel, voltage dependent, Kv4
 IPR004054  Potassium channel, voltage dependent, Kv4.1
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR021645  Shal-type voltage-gated potassium channels, N-terminal
 IPR024587  Potassium channel, voltage dependent, Kv4, C-terminal
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005250 A-type (transient outward) potassium channel activity IBA
 molecular_functionGO:0005267 potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Phase 1 - inactivation of fast Na+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000034808 kcnip1b / Kv channel interacting protein 1 b / KCNIP1* / Q9JJ57* / Q9NZI2* / Kv channel-interacting protein 1 * / potassium voltage-gated channel interacting protein 1*  / complex
 ENSDARG00000056101 kcnd3 / potassium voltage-gated channel, Shal-related subfamily, member 3 / Q9UK17* / Q9Z0V1* / potassium voltage-gated channel subfamily D member 3* / potassium voltage-gated channel, Shal...  / complex
 ENSDARG00000017880 kcnip3b / Kv channel interacting protein 3b, calsenilin / Q9Y2W7* / KCNIP3* / Q9QXT8* / Kv channel interacting protein 3, calsenilin* / potassium voltage-gated channel interacting protein 3*  / complex
 ENSDARG00000037256 si:ch211-145b13.5 / KCNIP4* / Q6PHZ8* / Q6PIL6* / Kv channel interacting protein 4* / potassium voltage-gated channel interacting protein 4*  / complex
 ENSDARG00000074746 kcnd1 / potassium voltage-gated channel, Shal-related subfamily, member 1 / Q03719* / Q9NSA2* / potassium voltage-gated channel subfamily D member 1*  / complex
 ENSDARG00000032799 kcnd2 / potassium voltage-gated channel, Shal-related subfamily, member 2 / Q9NZV8* / Q9Z0V2* / potassium voltage-gated channel subfamily D member 2*  / complex






 

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