ENSMUSG00000009731


Mus musculus

Features
Gene ID: ENSMUSG00000009731
  
Biological name :Kcnd1
  
Synonyms : Kcnd1 / Potassium voltage-gated channel subfamily D member 1 / Q03719
  
Possible biological names infered from orthology : Q9NSA2
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A1.1
Gene start: 7822289
Gene end: 7838280
  
Corresponding Affymetrix probe sets: 10598448 (MoGene1.0st)   1421538_at (Mouse Genome 430 2.0 Array)   1446556_at (Mouse Genome 430 2.0 Array)   1455514_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000009875
NCBI entrez gene - 16506     See in Manteia.
MGI - MGI:96671
RefSeq - NM_008423
RefSeq Peptide - NP_032449
swissprot - A2AEX0
swissprot - Q03719
Ensembl - ENSMUSG00000009731
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnd1ENSDARG00000074746Danio rerio
 KCND1ENSG00000102057Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnd2 / Q9Z0V2 / Potassium voltage-gated channel subfamily D member 2 / Q9NZV8*ENSMUSG0000006088266
Kcnd3 / Q9Z0V1 / potassium voltage-gated channel, Shal-related family, member 3 / Q9UK17* / potassium voltage-gated channel subfamily D member 3*ENSMUSG0000004089665
Kcnc3 / potassium voltage-gated channel subfamily C member 3 isoform 2 / Q14003* / potassium voltage-gated channel subfamily C member 3*ENSMUSG0000006278527
Kcna4 / Q61423 / Potassium voltage-gated channel subfamily A member 4 / P22459*ENSMUSG0000004260427
Kcna7 / Q17ST2 / Potassium voltage-gated channel subfamily A member 7 / Q96RP8*ENSMUSG0000003820127
Kcna5 / Q61762 / Potassium voltage-gated channel subfamily A member 5 / P22460*ENSMUSG0000004553427
Kcna3 / P16390 / Potassium voltage-gated channel subfamily A member 3 / P22001*ENSMUSG0000004795927
Kcna2 / P63141 / Potassium voltage-gated channel subfamily A member 2 / P16389*ENSMUSG0000004072427
Kcna1 / P16388 / Potassium voltage-gated channel subfamily A member 1 / Q09470*ENSMUSG0000004797626
Kcnc4 / Q8R1C0 / Potassium voltage-gated channel subfamily C member 4 / Q03721*ENSMUSG0000002789525
B2RQA1 / Kcna10 / Potassium voltage-gated channel subfamily A member 10 / Q16322*ENSMUSG0000004286125
Kcnc1 / P15388 / Potassium voltage-gated channel subfamily C member 1 / P48547*ENSMUSG0000005897525
Kcna6 / Q61923 / Potassium voltage-gated channel subfamily A member 6 / P17658*ENSMUSG0000003807725
Kcnc2 / Q14B80 / Potassium voltage-gated channel subfamily C member 2 / Q96PR1*ENSMUSG0000003568125


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003975  Potassium channel, voltage dependent, Kv4
 IPR004054  Potassium channel, voltage dependent, Kv4.1
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR021645  Shal-type voltage-gated potassium channels, N-terminal
 IPR024587  Potassium channel, voltage dependent, Kv4, C-terminal
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005250 A-type (transient outward) potassium channel activity IBA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Phase 1 - inactivation of fast Na+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000040896 Kcnd3 / Q9Z0V1 / potassium voltage-gated channel, Shal-related family, member 3 / Q9UK17* / potassium voltage-gated channel subfamily D member 3*  / complex
 ENSMUSG00000060882 Kcnd2 / Q9Z0V2 / Potassium voltage-gated channel subfamily D member 2 / Q9NZV8*  / complex
 ENSMUSG00000009731 Kcnd1 / Q03719 / Potassium voltage-gated channel subfamily D member 1 / Q9NSA2*  / complex
 ENSMUSG00000025221 Kcnip2 / Q9JJ69 / Kv channel-interacting protein 2 / Q9NS61* / potassium voltage-gated channel interacting protein 2*  / complex
 ENSMUSG00000079056 Kcnip3 / Q9QXT8 / Kv channel interacting protein 3, calsenilin / Q9Y2W7* / potassium voltage-gated channel interacting protein 3*  / complex
 ENSMUSG00000053519 Kcnip1 / Q9JJ57 / Kv channel-interacting protein 1 / Q9NZI2* / potassium voltage-gated channel interacting protein 1*  / complex
 ENSMUSG00000029088 Kcnip4 / Q6PHZ8 / Kv channel interacting protein 4 / Q6PIL6* / potassium voltage-gated channel interacting protein 4*  / complex






 

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