ENSMUSG00000042861


Mus musculus

Features
Gene ID: ENSMUSG00000042861
  
Biological name :Kcna10
  
Synonyms : B2RQA1 / Kcna10 / Potassium voltage-gated channel subfamily A member 10
  
Possible biological names infered from orthology : Q16322
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.3
Gene start: 107183056
Gene end: 107195721
  
Corresponding Affymetrix probe sets: 10495199 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000088118
NCBI entrez gene - 242151     See in Manteia.
MGI - MGI:3037820
RefSeq - NM_001081140
RefSeq Peptide - NP_001074609
swissprot - B2RQA1
Ensembl - ENSMUSG00000042861
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNA10ENSGALG00000000441Gallus gallus
 KCNA10ENSG00000143105Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcna5 / Q61762 / Potassium voltage-gated channel subfamily A member 5 / P22460*ENSMUSG0000004553461
Kcna3 / P16390 / Potassium voltage-gated channel subfamily A member 3 / P22001*ENSMUSG0000004795959
Kcna4 / Q61423 / Potassium voltage-gated channel subfamily A member 4 / P22459*ENSMUSG0000004260459
Kcna2 / P63141 / Potassium voltage-gated channel subfamily A member 2 / P16389*ENSMUSG0000004072458
Kcna1 / P16388 / Potassium voltage-gated channel subfamily A member 1 / Q09470*ENSMUSG0000004797658
Kcna6 / Q61923 / Potassium voltage-gated channel subfamily A member 6 / P17658*ENSMUSG0000003807757
Kcna7 / Q17ST2 / Potassium voltage-gated channel subfamily A member 7 / Q96RP8*ENSMUSG0000003820153
Kcnc2 / Q14B80 / Potassium voltage-gated channel subfamily C member 2 / Q96PR1*ENSMUSG0000003568134
Kcnc4 / Q8R1C0 / Potassium voltage-gated channel subfamily C member 4 / Q03721*ENSMUSG0000002789534
Kcnc3 / potassium voltage-gated channel subfamily C member 3 isoform 2 / Q14003* / potassium voltage-gated channel subfamily C member 3*ENSMUSG0000006278534
Kcnc1 / P15388 / Potassium voltage-gated channel subfamily C member 1 / P48547*ENSMUSG0000005897532
Kcnd3 / Q9Z0V1 / potassium voltage-gated channel, Shal-related family, member 3 / Q9UK17* / potassium voltage-gated channel subfamily D member 3*ENSMUSG0000004089632
Kcnd2 / Q9Z0V2 / Potassium voltage-gated channel subfamily D member 2 / Q9NZV8*ENSMUSG0000006088232
Kcnd1 / Q03719 / Potassium voltage-gated channel subfamily D member 1 / Q9NSA2*ENSMUSG0000000973131


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003972  Potassium channel, voltage dependent, Kv1
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport ISO
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity ISO
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004812 abnormal linear vestibular evoked potential "anomaly in the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head); normally, this response is measured by electrophysiological activity of the peripheral vestibular nerve; this assesses the function of the gravity receptor system including the utricles and saccules of the inner ear" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdkl5tm1.2Cogr/Cdkl5+,Tg(Thy1-YFP)#Jrs/0
Genetic Background: involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA

 MP:0004813 absent linear vestibular evoked potential "absence of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdkl5tm1.2Cogr/Cdkl5+,Tg(Thy1-YFP)#Jrs/0
Genetic Background: involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Cdkl5tm1.2Cogr/Cdkl5+,Tg(Thy1-YFP)#Jrs/0
Genetic Background: involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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