ENSDARG00000074802


Danio rerio

Features
Gene ID: ENSDARG00000074802
  
Biological name :cflarb
  
Synonyms : CASP8 and FADD-like apoptosis regulator b / cflarb
  
Possible biological names infered from orthology : CASP8 and FADD like apoptosis regulator / CASP8 and FADD-like apoptosis regulator CASP8 and FADD-like apoptosis regulator subunit p43 CASP8 and FADD-like apoptosis regulator subunit p12 / CFLAR / O15519 / O35732
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 701452
Gene end: 704667
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000122860
swissprot - F1QQS7
ZFIN ID - ZDB-GENE-091204-464
Ensembl - ENSDARG00000074802
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CFLARENSGALG00000008240Gallus gallus
 CFLARENSG00000003402Homo sapiens
 CflarENSMUSG00000026031Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cflara / CASP8 and FADD-like apoptosis regulator a / CFLAR* / O35732* / O15519* / CASP8 and FADD like apoptosis regulator* / CASP8 and FADD-like apoptosis regulator CASP8 and FADD-like apop...ENSDARG0000005596642


Protein motifs (from Interpro)
Interpro ID Name
 IPR001875  Death effector domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042981 regulation of apoptotic process IEA


Pathways (from Reactome)
Pathway description
Regulation by c-FLIP
RIPK1-mediated regulated necrosis
CASP8 activity is inhibited
Dimerization of procaspase-8
TRAIL signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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