ENSDARG00000074876


Danio rerio

Features
Gene ID: ENSDARG00000074876
  
Biological name :abcd1
  
Synonyms : abcd1 / ATP-binding cassette, sub-family D (ALD), member 1
  
Possible biological names infered from orthology : ATP binding cassette subfamily D member 1 / P33897 / P48410
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 8046086
Gene end: 8084343
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101144
Ensembl peptide - ENSDARP00000137751
NCBI entrez gene - 566367     See in Manteia.
RefSeq - NM_001111186
RefSeq Peptide - NP_001104656
swissprot - F1RBC8
swissprot - A9JRC4
ZFIN ID - ZDB-GENE-050517-27
Ensembl - ENSDARG00000074876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCD1ENSG00000101986Homo sapiens
 Abcd1ENSMUSG00000031378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcd2 / ATP-binding cassette, sub-family D (ALD), member 2 / Q9UBJ2* / ATP binding cassette subfamily D member 2*ENSDARG0000005940940
abcd3a / ATP-binding cassette, sub-family D (ALD), member 3a / ABCD3* / P55096* / P28288* / ATP binding cassette subfamily D member 3* / ATP-binding cassette, sub-family D (ALD), member 3*ENSDARG0000010408531
abcd3b / ATP-binding cassette, sub-family D (ALD), member 3b / ABCD3* / P55096* / P28288* / ATP binding cassette subfamily D member 3* / ATP-binding cassette, sub-family D (ALD), member 3*ENSDARG0000000294731
abcd4 / ATP-binding cassette, sub-family D (ALD), member 4 / O14678* / O89016* / ATP binding cassette subfamily D member 4*ENSDARG0000006177021


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031237  ATP-binding cassette sub-family D member 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0030301 cholesterol transport IMP
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Beta-oxidation of very long chain fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism cholesterol increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002947 abcd3b / ATP-binding cassette, sub-family D (ALD), member 3b / ABCD3* / P55096* / P28288* / ATP binding cassette subfamily D member 3* / ATP-binding cassette, sub-family D (ALD), member 3*  / complex
 ENSDARG00000074876 abcd1 / ATP-binding cassette, sub-family D (ALD), member 1 / P33897* / P48410* / ATP binding cassette subfamily D member 1*  / complex
 ENSDARG00000059409 abcd2 / ATP-binding cassette, sub-family D (ALD), member 2 / Q9UBJ2* / ATP binding cassette subfamily D member 2*  / complex






 

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