ENSDARG00000075672


Danio rerio

Features
Gene ID: ENSDARG00000075672
  
Biological name :pms2
  
Synonyms : PMS1 homolog 2, mismatch repair system component / pms2
  
Possible biological names infered from orthology : Gm42421 / P54278
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 17603528
Gene end: 17619524
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099444
NCBI entrez gene - 565276     See in Manteia.
RefSeq - XM_021480287
RefSeq - XM_688556
swissprot - E7F558
ZFIN ID - ZDB-GENE-030131-686
Ensembl - ENSDARG00000075672
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PMS2ENSGALG00000003430Gallus gallus
 PMS2ENSG00000122512Homo sapiens
 Gm42421ENSMUSG00000104633Mus musculus
 Pms2ENSMUSG00000079109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pms1 / PMS1 homolog 1, mismatch repair system component / P54277*ENSDARG0000000047620


Protein motifs (from Interpro)
Interpro ID Name
 IPR002099  DNA mismatch repair protein family, N-terminal
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR013507  DNA mismatch repair protein, S5 domain 2-like
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR014762  DNA mismatch repair, conserved site
 IPR014790  MutL, C-terminal, dimerisation
 IPR020568  Ribosomal protein S5 domain 2-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006298 mismatch repair IBA
 biological_processGO:0016446 somatic hypermutation of immunoglobulin genes IBA
 cellular_componentGO:0032389 MutLalpha complex IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0030983 mismatched DNA binding IEA


Pathways (from Reactome)
Pathway description
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / reaction / complex






 

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