ENSDARG00000075758


Danio rerio

Features
Gene ID: ENSDARG00000075758
  
Biological name :ywhabb
  
Synonyms : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b / ywhabb
  
Possible biological names infered from orthology : P31946 / Q9CQV8 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide / YWHAB
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 45418985
Gene end: 45430942
  
Corresponding Affymetrix probe sets: Dr.5301.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101100
Ensembl peptide - ENSDARP00000123950
swissprot - F1RBF6
swissprot - F8W493
ZFIN ID - ZDB-GENE-040426-2160
Ensembl - ENSDARG00000075758
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 YWHABENSGALG00000004143Gallus gallus
 YWHABENSG00000166913Homo sapiens
 YwhabENSMUSG00000018326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat...ENSDARG0000001307894
ywhabl / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide likeENSDARG0000004028782
ywhaqa / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...ENSDARG0000004253981
ywhaqb / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...ENSDARG0000002332380
ywhag2 / 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2 / YWHAG* / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation pro...ENSDARG0000007165876
ywhag1 / Q6PC29 / 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 / YWHAG* / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activ...ENSDARG0000006762676
ywhaz / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptideENSDARG0000003257576
ywhah / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide / P68510* / Q04917* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta*ENSDARG0000000556072
ywhae1 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 / YWHAE* / P62259* / P62258* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase act...ENSDARG0000000639969
ywhae2 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2ENSDARG0000001701467


Protein motifs (from Interpro)
Interpro ID Name
 IPR000308  14-3-3 protein
 IPR023409  14-3-3 protein, conserved site
 IPR023410  14-3-3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
mTOR signalling
mTORC1-mediated signalling
Signaling by Hippo
Rap1 signalling
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
TP53 Regulates Metabolic Genes
RAF activation
MAP2K and MAPK activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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