ENSDARG00000005560


Danio rerio

Features
Gene ID: ENSDARG00000005560
  
Biological name :ywhah
  
Synonyms : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide / ywhah
  
Possible biological names infered from orthology : P68510 / Q04917 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 17166035
Gene end: 17170086
  
Corresponding Affymetrix probe sets: Dr.1524.1.S1_at (Zebrafish Array)   NM_213164_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000008690
NCBI entrez gene - 406443     See in Manteia.
RefSeq - NM_213164
RefSeq Peptide - NP_998329
swissprot - Q7T3G2
ZFIN ID - ZDB-GENE-040426-2191
Ensembl - ENSDARG00000005560
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 YWHAHENSGALG00000006743Gallus gallus
 YWHAHENSG00000128245Homo sapiens
 YwhahENSMUSG00000018965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ywhag1 / Q6PC29 / 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 / YWHAG* / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activ...ENSDARG0000006762685
ywhag2 / 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2 / YWHAG* / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation pro...ENSDARG0000007165884
ywhabb / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b / YWHAB* / Q9CQV8* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activa...ENSDARG0000007575871
ywhaqb / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...ENSDARG0000002332370
ywhaqa / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...ENSDARG0000004253970
ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat...ENSDARG0000001307870
ywhabl / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide likeENSDARG0000004028768
ywhaz / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptideENSDARG0000003257567
ywhae2 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2ENSDARG0000001701463
ywhae1 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 / YWHAE* / P62259* / P62258* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase act...ENSDARG0000000639962


Protein motifs (from Interpro)
Interpro ID Name
 IPR000308  14-3-3 protein
 IPR023409  14-3-3 protein, conserved site
 IPR023410  14-3-3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000005560 ywhah / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide / P68510* / Q04917* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta*  / complex






 

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