ENSDARG00000042539


Danio rerio

Features
Gene ID: ENSDARG00000042539
  
Biological name :ywhaqa
  
Synonyms : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a / ywhaqa
  
Possible biological names infered from orthology : O70456 / P27348 / P31947 / P68254 / SFN / stratifin / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta / YWHAQ
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 29565906
Gene end: 29585336
  
Corresponding Affymetrix probe sets: Dr.4609.1.S1_at (Zebrafish Array)   Dr.4609.1.S2_at (Zebrafish Array)   NM_201513_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062382
NCBI entrez gene - 399487     See in Manteia.
RefSeq - NM_201513
RefSeq Peptide - NP_958921
swissprot - Q7ZUM0
ZFIN ID - ZDB-GENE-040122-5
Ensembl - ENSDARG00000042539
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SFNENSGALG00000028115Gallus gallus
 YWHAQENSGALG00000016433Gallus gallus
 SFNENSG00000175793Homo sapiens
 YWHAQENSG00000134308Homo sapiens
 SfnENSMUSG00000047281Mus musculus
 YwhaqENSMUSG00000076432Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ywhaqb / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...ENSDARG0000002332389
ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat...ENSDARG0000001307881
ywhabb / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b / YWHAB* / Q9CQV8* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activa...ENSDARG0000007575880
ywhabl / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide likeENSDARG0000004028778
ywhaz / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptideENSDARG0000003257575
ywhag1 / Q6PC29 / 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 / YWHAG* / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activ...ENSDARG0000006762671
ywhag2 / 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2 / YWHAG* / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation pro...ENSDARG0000007165871
ywhah / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide / P68510* / Q04917* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta*ENSDARG0000000556071
ywhae2 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2ENSDARG0000001701464
ywhae1 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 / YWHAE* / P62259* / P62258* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase act...ENSDARG0000000639964


Protein motifs (from Interpro)
Interpro ID Name
 IPR000308  14-3-3 protein
 IPR023409  14-3-3 protein, conserved site
 IPR023410  14-3-3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
TP53 Regulates Metabolic Genes
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000023323 ywhaqb / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...  / complex / reaction
 ENSDARG00000042539 ywhaqa / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a / SFN* / YWHAQ* / P27348* / P31947* / P68254* / O70456* / stratifin* / tyrosine 3-monoox...  / reaction / complex
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction / complex






 

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