ENSGALG00000028115


Gallus gallus

Features
Gene ID: ENSGALG00000028115
  
Biological name :SFN
  
Synonyms : SFN / stratifin
  
Possible biological names infered from orthology : O70456 / P31947
  
Species: Gallus gallus
  
Chr. number: 23
Strand: 1
Band:
Gene start: 1821477
Gene end: 1822271
  
Corresponding Affymetrix probe sets: Gga.17688.1.A1_at (Chicken Array)   Gga.17688.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040672
NCBI entrez gene - 408037     See in Manteia.
RefSeq - NM_001293176
RefSeq Peptide - NP_001280105
swissprot - R4GF89
Ensembl - ENSGALG00000028115
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ywhaqaENSDARG00000042539Danio rerio
 ywhaqbENSDARG00000023323Danio rerio
 SFNENSG00000175793Homo sapiens
 SfnENSMUSG00000047281Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
YWHAZ / Q5ZKC9 / 14-3-3 protein zeta / P63104* / P63101* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenas...ENSGALG0000003138771
YWHAB / Q5ZLQ6 / 14-3-3 protein beta/alpha / Q9CQV8* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta* / tyrosine 3-monooxygenase/tryptophan 5-monoox...ENSGALG0000000414368
YWHAQ / Q5ZMD1 / 14-3-3 protein theta / P68254* / P27348* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta*ENSGALG0000001643367
YWHAG / 14-3-3 protein gamma / P61982* / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activ...ENSGALG0000001735865
YWHAH / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta / P68510* / Q04917* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide*ENSGALG0000000674363
YWHAE / Q5ZMT0 / 14-3-3 protein epsilon / P62259* / P62258* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon* / tyrosine 3-monooxygenase/tryptophan 5-monoox...ENSGALG0000000266160


Protein motifs (from Interpro)
Interpro ID Name
 IPR000308  14-3-3 protein
 IPR023409  14-3-3 protein, conserved site
 IPR023410  14-3-3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0001836 release of cytochrome c from mitochondria IEA
 biological_processGO:0003334 keratinocyte development IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0010482 regulation of epidermal cell division IEA
 biological_processGO:0010839 negative regulation of keratinocyte proliferation IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0031424 keratinization IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0045606 positive regulation of epidermal cell differentiation IEA
 biological_processGO:0046827 positive regulation of protein export from nucleus IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0061436 establishment of skin barrier IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
TP53 Regulates Metabolic Genes
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000028115 SFN / stratifin / O70456* / P31947*  / reaction / complex






 

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