ENSDARG00000076121


Danio rerio

Features
Gene ID: ENSDARG00000076121
  
Biological name :smpd1
  
Synonyms : smpd1 / sphingomyelin phosphodiesterase 1, acid lysosomal
  
Possible biological names infered from orthology : P17405 / Q04519 / sphingomyelin phosphodiesterase 1
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 24709967
Gene end: 24724388
  
Corresponding Affymetrix probe sets: Dr.2422.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124101
swissprot - F8W546
ZFIN ID - ZDB-GENE-110411-222
Ensembl - ENSDARG00000076121
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMPD1ENSGALG00000036106Gallus gallus
 SMPD1ENSG00000166311Homo sapiens
 Smpd1ENSMUSG00000037049Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smpdl3b / sphingomyelin phosphodiesterase, acid-like 3B / P58242* / Q92485*ENSDARG0000001013017
smpdl3a / sphingomyelin phosphodiesterase, acid-like 3A / Q92484*ENSDARG0000005311916


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR008139  Saposin B type domain
 IPR011001  Saposin-like
 IPR011160  Sphingomyelin phosphodiesterase
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006685 sphingomyelin catabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004767 sphingomyelin phosphodiesterase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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