ENSGALG00000036106


Gallus gallus

Features
Gene ID: ENSGALG00000036106
  
Biological name :SMPD1
  
Synonyms : SMPD1 / sphingomyelin phosphodiesterase 1
  
Possible biological names infered from orthology : P17405 / Q04519 / sphingomyelin phosphodiesterase 1, acid lysosomal
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 194449530
Gene end: 194453332
  
Corresponding Affymetrix probe sets: GgaAffx.11117.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049247
NCBI entrez gene - 419077     See in Manteia.
RefSeq - XM_015280935
swissprot - A0A1D5P946
Ensembl - ENSGALG00000036106
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smpd1ENSDARG00000076121Danio rerio
 SMPD1ENSG00000166311Homo sapiens
 Smpd1ENSMUSG00000037049Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P70158* / Q92484* / SMPDL3A* / sphingomyelin phosphodiesterase acid like 3A*ENSGALG0000003027521
SMPDL3B / sphingomyelin phosphodiesterase acid like 3B / P58242* / Q92485*ENSGALG0000000073720


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR008139  Saposin B type domain
 IPR011160  Sphingomyelin phosphodiesterase
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006685 sphingomyelin catabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0023021 termination of signal transduction IEA
 biological_processGO:0035307 positive regulation of protein dephosphorylation IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0046513 ceramide biosynthetic process IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0004767 sphingomyelin phosphodiesterase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061750 acid sphingomyelin phosphodiesterase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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