ENSDARG00000076466


Danio rerio

Features
Gene ID: ENSDARG00000076466
  
Biological name :maml1
  
Synonyms : maml1 / mastermind-like transcriptional coactivator 1
  
Possible biological names infered from orthology : Mastermind-like protein 1 / Q6T264 / Q92585
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 16382507
Gene end: 16423203
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000102289
Ensembl peptide - ENSDARP00000134496
NCBI entrez gene - 567335     See in Manteia.
swissprot - A0A0R4IKI2
swissprot - E7F0M7
ZFIN ID - ZDB-GENE-100820-2
Ensembl - ENSDARG00000076466
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAML1ENSGALG00000005929Gallus gallus
 MAML1ENSG00000161021Homo sapiens
 Maml1ENSMUSG00000050567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
maml3 / mastermind-like transcriptional coactivator 3 / Q96JK9*ENSDARG0000007955220
CABZ01061591.1 / MAML2* / Q8IZL2* / mastermind like transcriptional coactivator 2*ENSDARG0000011297715


Protein motifs (from Interpro)
Interpro ID Name
 IPR019082  Neurogenic mastermind-like, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007221 positive regulation of transcription of Notch receptor target IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA


Pathways (from Reactome)
Pathway description
NOTCH2 intracellular domain regulates transcription
RUNX3 regulates NOTCH signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003398 rbpja / recombination signal binding protein for immunoglobulin kappa J region a / RBPJ* / Q06330* / recombination signal binding protein for immunoglobulin kappa J region*  / reaction / complex
 ENSDARG00000052091 rbpjb / recombination signal binding protein for immunoglobulin kappa J region b / RBPJ* / Q06330* / P31266* / Recombining binding protein suppressor of hairless * / recombination signal bi...  / reaction / complex
 ENSDARG00000104329 si:ch73-281k2.5 / NOTCH2* / Q04721*  / complex / reaction
 ENSDARG00000043130 notch2 / Q04721*  / complex / reaction






 

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