ENSDARG00000104329


Danio rerio

Features
Gene ID: ENSDARG00000104329
  
Biological name :si:ch73-281k2.5
  
Synonyms : si:ch73-281k2.5
  
Possible biological names infered from orthology : NOTCH2 / Q04721
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 19514294
Gene end: 19520341
  
Corresponding Affymetrix probe sets: Dr.16720.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000137271
NCBI entrez gene - 100002182     See in Manteia.
swissprot - A0A0R4IN59
ZFIN ID - ZDB-GENE-141222-10
Ensembl - ENSDARG00000104329
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NOTCH2ENSGALG00000002922Gallus gallus
 NOTCH2ENSG00000134250Homo sapiens
 Notch2ENSMUSG00000027878Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
notch2 / Q04721*ENSDARG0000004313080
notch1b / NOTCH1* / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSDARG0000005209462
notch3 / Q9UM47*ENSDARG0000005213961
notch1a / NOTCH1* / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSDARG0000010355459
jag1a / jagged 1a / JAG1* / P78504* / jagged 1*ENSDARG0000003028923
jag2a / jagged 2a / JAG2* / Q9Y219* / jagged 2*ENSDARG0000001424623
jag1b / jagged 1b / JAG1* / P78504* / Q9QXX0* / jagged 1* / Protein jagged-1 *ENSDARG0000001316823
jag2b / jagged 2b / JAG2* / Q9QYE5* / Q9Y219* / jagged 2* / Protein jagged-2 *ENSDARG0000002138921
dlc / deltaCENSDARG0000000233616
sned1 / sushi, nidogen and EGF-like domains 1 / Q8TER0*ENSDARG0000004443316
dla / deltaA / DLL1* / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSDARG0000001079116
dld / deltaD / DLL1* / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSDARG0000002021916
dlb / deltaB / O57409ENSDARG0000000423215
dll4 / delta-like 4 (Drosophila) / Q9JI71* / Q9NR61* / Delta-like protein 4 * / delta like canonical Notch ligand 4*ENSDARG0000007042515


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Pre-NOTCH Processing in Golgi
NOTCH2 intracellular domain regulates transcription
NOTCH2 Activation and Transmission of Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003398 rbpja / recombination signal binding protein for immunoglobulin kappa J region a / RBPJ* / Q06330* / recombination signal binding protein for immunoglobulin kappa J region*  / reaction / complex
 ENSDARG00000043130 notch2 / Q04721*  / complex
 ENSDARG00000052091 rbpjb / recombination signal binding protein for immunoglobulin kappa J region b / RBPJ* / Q06330* / P31266* / Recombining binding protein suppressor of hairless * / recombination signal bi...  / complex / reaction
 ENSDARG00000076466 maml1 / mastermind-like transcriptional coactivator 1 / Q6T264* / Q92585* / Mastermind-like protein 1 *  / reaction / complex
 ENSDARG00000079552 maml3 / mastermind-like transcriptional coactivator 3 / Q96JK9*  / complex / reaction
 ENSDARG00000104329 si:ch73-281k2.5 / NOTCH2* / Q04721*  / complex






 

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