ENSDARG00000030289


Danio rerio

Features
Gene ID: ENSDARG00000030289
  
Biological name :jag1a
  
Synonyms : jag1a / jagged 1a
  
Possible biological names infered from orthology : JAG1 / jagged 1 / P78504 / Protein jagged-1 / Q9QXX0
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 51104984
Gene end: 51157660
  
Corresponding Affymetrix probe sets: Dr.12590.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000121170
Ensembl peptide - ENSDARP00000047850
NCBI entrez gene - 140421     See in Manteia.
RefSeq - XM_005168204
swissprot - F1QP77
swissprot - B8JKQ5
ZFIN ID - ZDB-GENE-011128-2
Ensembl - ENSDARG00000030289
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 JAG1ENSGALG00000009020Gallus gallus
 JAG1ENSG00000101384Homo sapiens
 Jag1ENSMUSG00000027276Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
jag1b / jagged 1b / JAG1* / P78504* / Q9QXX0* / jagged 1* / Protein jagged-1 *ENSDARG0000001316869
jag2b / jagged 2b / JAG2* / Q9QYE5* / Q9Y219* / jagged 2* / Protein jagged-2 *ENSDARG0000002138950
jag2a / jagged 2a / JAG2* / Q9Y219* / jagged 2*ENSDARG0000001424646
notch1a / NOTCH1* / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSDARG0000010355428
notch2 / Q04721*ENSDARG0000004313027
notch1b / NOTCH1* / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSDARG0000005209427
notch3 / Q9UM47*ENSDARG0000005213927
dld / deltaD / DLL1* / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSDARG0000002021918
dla / deltaA / DLL1* / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSDARG0000001079118
sned1 / sushi, nidogen and EGF-like domains 1 / Q8TER0*ENSDARG0000004443318
dlc / deltaCENSDARG0000000233616
dll4 / delta-like 4 (Drosophila) / Q9JI71* / Q9NR61* / Delta-like protein 4 * / delta like canonical Notch ligand 4*ENSDARG0000007042516
dlb / deltaB / O57409ENSDARG0000000423215
si:ch73-281k2.5 / NOTCH2* / Q04721*ENSDARG000001043295


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001007  VWFC domain
 IPR001774  Delta/Serrate/lag-2 (DSL) protein
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011651  Notch ligand, N-terminal domain
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026219  Jagged/Serrate protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005112 Notch binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
NOTCH3 Activation and Transmission of Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

 ZFA:0001158 endocrine system endocrine system has fewer parts of type thyroid follicle , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage decreased size , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased size , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta decreased amount , abnormal
Show

 ZFA:0009354 hematopoietic multipotent progenitor cell hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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