ENSDARG00000002336


Danio rerio

Features
Gene ID: ENSDARG00000002336
  
Biological name :dlc
  
Synonyms : deltaC / dlc
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 20463448
Gene end: 20468302
  
Corresponding Affymetrix probe sets: Dr.16183.1.S1_at (Zebrafish Array)   Dr.8086.1.S1_at (Zebrafish Array)   Dr.8086.1.S1_s_at (Zebrafish Array)   NM_130944_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018643
NCBI entrez gene - 30120     See in Manteia.
RefSeq - NM_130944
RefSeq Peptide - NP_571019
swissprot - B3DFM3
ZFIN ID - ZDB-GENE-000125-4
Ensembl - ENSDARG00000002336
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dlb / deltaB / O57409ENSDARG0000000423256
dla / deltaA / DLL1* / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSDARG0000001079148
dld / deltaD / DLL1* / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSDARG0000002021948
dll4 / delta-like 4 (Drosophila) / Q9JI71* / Q9NR61* / Delta-like protein 4 * / delta like canonical Notch ligand 4*ENSDARG0000007042546
jag2b / jagged 2b / JAG2* / Q9QYE5* / Q9Y219* / jagged 2* / Protein jagged-2 *ENSDARG0000002138931
jag1a / jagged 1a / JAG1* / P78504* / jagged 1*ENSDARG0000003028931
jag1b / jagged 1b / JAG1* / P78504* / Q9QXX0* / jagged 1* / Protein jagged-1 *ENSDARG0000001316830
jag2a / jagged 2a / JAG2* / Q9Y219* / jagged 2*ENSDARG0000001424630
notch1a / NOTCH1* / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSDARG0000010355429
notch1b / NOTCH1* / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSDARG0000005209429
notch3 / Q9UM47*ENSDARG0000005213928
notch2 / Q04721*ENSDARG0000004313027
sned1 / sushi, nidogen and EGF-like domains 1 / Q8TER0*ENSDARG0000004443319
si:ch73-281k2.5 / NOTCH2* / Q04721*ENSDARG000001043296


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001774  Delta/Serrate/lag-2 (DSL) protein
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood decreased amount , abnormal
Show

 ZFA:0000073 somite 5 somite 5 somite border amorphous , abnormal
Show

 ZFA:0000155 somite somite quality , abnormal
somite shape , abnormal
somite anatomical boundary morphology , abnormal
somite morphology , abnormal
Show

 ZFA:0000733 somite 7 somite 7 somite border amorphous , abnormal
Show

 ZFA:0000858 somite 8 somite 8 somite border amorphous , abnormal
Show

 ZFA:0000982 somite 6 somite 6 somite border amorphous , abnormal
Show

 ZFA:0000983 somite 9 somite 9 somite border amorphous , abnormal
Show

 ZFA:0001117 post-vent region post-vent region quality , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
Show

 ZFA:0001462 somite border somite border irregular spatial pattern , abnormal
somite border deformed , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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