ENSDARG00000076933


Danio rerio

Features
Gene ID: ENSDARG00000076933
  
Biological name :aldh1a3
  
Synonyms : aldehyde dehydrogenase 1 family, member A3 / aldh1a3
  
Possible biological names infered from orthology : Aldehyde dehydrogenase family 1 member A3 / P47895 / Q9JHW9
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 9721385
Gene end: 9803154
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000055592
NCBI entrez gene - 751785     See in Manteia.
swissprot - Q0H2G3
ZFIN ID - ZDB-GENE-061128-2
Ensembl - ENSDARG00000076933
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALDH1A3ENSGALG00000033365Gallus gallus
 P47895ENSG00000184254Homo sapiens
 Q9JHW9ENSMUSG00000015134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aldh1a2 / aldehyde dehydrogenase 1 family, member A2 / O94788* / Q62148* / Retinal dehydrogenase 2 *ENSDARG0000005349365
aldh2.2 / aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2 / ALDH2* / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSDARG0000002808758
aldh2.1 / aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 / ALDH2* / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSDARG0000008992458
aldh1l2 / aldehyde dehydrogenase 1 family, member L2 / Q3SY69* / Q8K009* / Mitochondrial 10-formyltetrahydrofolate dehydrogenase *ENSDARG0000007023047
aldh1l1 / aldehyde dehydrogenase 1 family, member L1 / O75891*ENSDARG0000007700446
Q66I21 / aldh8a1 / aldehyde dehydrogenase 8 family, member A1 / Q8BH00* / Q9H2A2* / Aldehyde dehydrogenase family 8 member A1 *ENSDARG0000003677637
Q7ZVB2 / aldh9a1a.1 / aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000006910035
Q802W2 / aldh9a1b / aldehyde dehydrogenase 9 family, member A1b / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000003706134
aldh9a1a.2 / aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2 / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000005533134
aldh7a1 / aldehyde dehydrogenase 7 family, member A1 / P49419* / Q9DBF1* / Alpha-aminoadipic semialdehyde dehydrogenase *ENSDARG0000001842628


Protein motifs (from Interpro)
Interpro ID Name
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased amount , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary absent , abnormal
midbrain hindbrain boundary present , ameliorated
midbrain hindbrain boundary decreased amount , abnormal
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 ZFA:0000107 eye eye size , ameliorated
eye decreased size , abnormal
eye decreased amount , abnormal
Show

 ZFA:0000109 forebrain forebrain decreased amount , abnormal
Show

 ZFA:0000152 retina retina decreased amount , abnormal
Show

 ZFA:0001031 rhombomere 1 rhombomere 1 decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076933 aldh1a3 / aldehyde dehydrogenase 1 family, member A3 / P47895* / Q9JHW9* / Aldehyde dehydrogenase family 1 member A3 *  / complex






 

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