ENSGALG00000033365


Gallus gallus

Features
Gene ID: ENSGALG00000033365
  
Biological name :ALDH1A3
  
Synonyms : aldehyde dehydrogenase 1 family member A3 / ALDH1A3
  
Possible biological names infered from orthology : Aldehyde dehydrogenase family 1 member A3 / P47895 / Q9JHW9
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 17449825
Gene end: 17484802
  
Corresponding Affymetrix probe sets: Gga.3807.1.S2_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055216
NCBI entrez gene - 395389     See in Manteia.
RefSeq - NM_204669
RefSeq Peptide - NP_990000
swissprot - Q9DD46
Ensembl - ENSGALG00000033365
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh1a3ENSDARG00000076933Danio rerio
 P47895ENSG00000184254Homo sapiens
 Q9JHW9ENSMUSG00000015134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALDH1A1 / retinal dehydrogenase 1 / O35945* / P00352* / P24549* / Aldh1a7* / Aldehyde dehydrogenase, cytosolic 1 * / aldehyde dehydrogenase 1 family member A1*ENSGALG0000001514770
O93344 / ALDH1A2 / Retinal dehydrogenase 2 / O94788* / Q62148* / aldehyde dehydrogenase 1 family member A2*ENSGALG0000000427069
ALDH2* / P05091* / P47738* / AC002996.1* / Aldehyde dehydrogenase, mitochondrial * / aldehyde dehydrogenase 2 family (mitochondrial)*ENSGALG0000000472563
ALDH1L2 / aldehyde dehydrogenase 1 family member L2 / Q3SY69* / Q8K009* / Mitochondrial 10-formyltetrahydrofolate dehydrogenase *ENSGALG0000001269146
ALDH8A1 / aldehyde dehydrogenase 8 family member A1 / Q8BH00* / Q9H2A2* / Aldehyde dehydrogenase family 8 member A1 *ENSGALG0000001396937
P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSGALG0000000349536
ALDH7A1 / aldehyde dehydrogenase 7 family member A1 / P49419* / Q9DBF1* / Alpha-aminoadipic semialdehyde dehydrogenase *ENSGALG0000000822929


Protein motifs (from Interpro)
Interpro ID Name
 IPR012394  Aldehyde dehydrogenase NAD(P)-dependent
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR016163  Aldehyde dehydrogenase, C-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002072 optic cup morphogenesis involved in camera-type eye development IEA
 biological_processGO:0002138 retinoic acid biosynthetic process IEA
 biological_processGO:0006081 cellular aldehyde metabolic process IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0021768 nucleus accumbens development IEA
 biological_processGO:0031076 embryonic camera-type eye development IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0042573 retinoic acid metabolic process IEA
 biological_processGO:0042574 retinal metabolic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043584 nose development IEA
 biological_processGO:0048048 embryonic eye morphogenesis IEA
 biological_processGO:0048386 positive regulation of retinoic acid receptor signaling pathway IDA
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060013 righting reflex IEA
 biological_processGO:0060166 olfactory pit development IEA
 biological_processGO:0060324 face development IEA
 biological_processGO:0070384 Harderian gland development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0001758 retinal dehydrogenase activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IEA
 molecular_functionGO:0004030 aldehyde dehydrogenase [NAD(P)+] activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0070324 thyroid hormone binding IEA
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000033365 ALDH1A3 / aldehyde dehydrogenase 1 family member A3 / P47895* / Q9JHW9* / Aldehyde dehydrogenase family 1 member A3 *  / complex






 

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