ENSGALG00000012691


Gallus gallus

Features
Gene ID: ENSGALG00000012691
  
Biological name :ALDH1L2
  
Synonyms : aldehyde dehydrogenase 1 family member L2 / ALDH1L2
  
Possible biological names infered from orthology : Mitochondrial 10-formyltetrahydrofolate dehydrogenase / Q3SY69 / Q8K009
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 54341803
Gene end: 54369311
  
Corresponding Affymetrix probe sets: Gga.11316.1.S1_at (Chicken Array)   Gga.11316.1.S1_s_at (Chicken Array)   GgaAffx.8040.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053762
Ensembl peptide - ENSGALP00000020685
NCBI entrez gene - 418078     See in Manteia.
RefSeq - XM_416314
RefSeq - XM_015287780
swissprot - F1P130
swissprot - A0A1D5PLP2
Ensembl - ENSGALG00000012691
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh1l2ENSDARG00000070230Danio rerio
 Q3SY69ENSG00000136010Homo sapiens
 Q8K009ENSMUSG00000020256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALDH1A1 / retinal dehydrogenase 1 / O35945* / P00352* / P24549* / Aldh1a7* / Aldehyde dehydrogenase, cytosolic 1 * / aldehyde dehydrogenase 1 family member A1*ENSGALG0000001514726
ALDH2* / P05091* / P47738* / AC002996.1* / Aldehyde dehydrogenase, mitochondrial * / aldehyde dehydrogenase 2 family (mitochondrial)*ENSGALG0000000472526
ALDH1A3 / aldehyde dehydrogenase 1 family member A3 / P47895* / Q9JHW9* / Aldehyde dehydrogenase family 1 member A3 *ENSGALG0000003336525
O93344 / ALDH1A2 / Retinal dehydrogenase 2 / O94788* / Q62148* / aldehyde dehydrogenase 1 family member A2*ENSGALG0000000427025
P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSGALG0000000349521
ALDH8A1 / aldehyde dehydrogenase 8 family member A1 / Q8BH00* / Q9H2A2* / Aldehyde dehydrogenase family 8 member A1 *ENSGALG0000001396919
ALDH7A1 / aldehyde dehydrogenase 7 family member A1 / P49419* / Q9DBF1* / Alpha-aminoadipic semialdehyde dehydrogenase *ENSGALG0000000822916


Protein motifs (from Interpro)
Interpro ID Name
 IPR001555  Phosphoribosylglycinamide formyltransferase, active site
 IPR002376  Formyl transferase, N-terminal
 IPR005793  Formyl transferase, C-terminal
 IPR006162  Phosphopantetheine attachment site
 IPR009081  Phosphopantetheine binding ACP domain
 IPR011034  Formyl transferase-like, C-terminal domain superfamily
 IPR011407  10-formyltetrahydrofolate dehydrogenase
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR016163  Aldehyde dehydrogenase, C-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0009258 10-formyltetrahydrofolate catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IBA
 molecular_functionGO:0016155 formyltetrahydrofolate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0016742 hydroxymethyl-, formyl- and related transferase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012691 ALDH1L2 / aldehyde dehydrogenase 1 family member L2 / Q3SY69* / Q8K009* / Mitochondrial 10-formyltetrahydrofolate dehydrogenase *  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr