ENSGALG00000004270


Gallus gallus

Features
Gene ID: ENSGALG00000004270
  
Biological name :ALDH1A2
  
Synonyms : ALDH1A2 / O93344 / Retinal dehydrogenase 2
  
Possible biological names infered from orthology : aldehyde dehydrogenase 1 family member A2 / O94788 / Q62148
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 7045146
Gene end: 7260351
  
Corresponding Affymetrix probe sets: Gga.2996.1.S2_at (Chicken Array)   Gga.2996.2.S1_a_at (Chicken Array)   GgaAffx.21394.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000060092
Ensembl peptide - ENSGALP00000033786
NCBI entrez gene - 395844     See in Manteia.
RefSeq - NM_204995
RefSeq Peptide - NP_990326
swissprot - O93344
swissprot - A0A1L1RMV7
swissprot - F1NIE7
Ensembl - ENSGALG00000004270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh1a2ENSDARG00000053493Danio rerio
 O94788ENSG00000128918Homo sapiens
 Q62148ENSMUSG00000013584Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALDH1A1 / retinal dehydrogenase 1 / O35945* / P00352* / P24549* / Aldh1a7* / Aldehyde dehydrogenase, cytosolic 1 * / aldehyde dehydrogenase 1 family member A1*ENSGALG0000001514772
ALDH1A3 / aldehyde dehydrogenase 1 family member A3 / P47895* / Q9JHW9* / Aldehyde dehydrogenase family 1 member A3 *ENSGALG0000003336568
ALDH2* / P05091* / P47738* / AC002996.1* / Aldehyde dehydrogenase, mitochondrial * / aldehyde dehydrogenase 2 family (mitochondrial)*ENSGALG0000000472565
ALDH1L2 / aldehyde dehydrogenase 1 family member L2 / Q3SY69* / Q8K009* / Mitochondrial 10-formyltetrahydrofolate dehydrogenase *ENSGALG0000001269146
P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSGALG0000000349537
ALDH8A1 / aldehyde dehydrogenase 8 family member A1 / Q8BH00* / Q9H2A2* / Aldehyde dehydrogenase family 8 member A1 *ENSGALG0000001396936
ALDH7A1 / aldehyde dehydrogenase 7 family member A1 / P49419* / Q9DBF1* / Alpha-aminoadipic semialdehyde dehydrogenase *ENSGALG0000000822927


Protein motifs (from Interpro)
Interpro ID Name
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR016163  Aldehyde dehydrogenase, C-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0001936 regulation of endothelial cell proliferation IEA
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009855 determination of bilateral symmetry IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014032 neural crest cell development IEA
 biological_processGO:0016331 morphogenesis of embryonic epithelium IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation IEP
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031076 embryonic camera-type eye development IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035799 ureter maturation IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0042573 retinoic acid metabolic process IEA
 biological_processGO:0042574 retinal metabolic process IEA
 biological_processGO:0042904 9-cis-retinoic acid biosynthetic process IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IEA
 biological_processGO:0048566 embryonic digestive tract development IEA
 biological_processGO:0048738 cardiac muscle tissue development IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060324 face development IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0001758 retinal dehydrogenase activity IEA
 molecular_functionGO:0004028 3-chloroallyl aldehyde dehydrogenase activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IBA
 molecular_functionGO:0004745 retinol dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004270 O93344 / ALDH1A2 / Retinal dehydrogenase 2 / O94788* / Q62148* / aldehyde dehydrogenase 1 family member A2*  / complex






 

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