ENSDARG00000078069


Danio rerio

Features
Gene ID: ENSDARG00000078069
  
Biological name :rrm2
  
Synonyms : P79733 / ribonucleotide reductase M2 polypeptide / rrm2
  
Possible biological names infered from orthology : AC007240.1 / P11157 / P31350 / Ribonucleoside-diphosphate reductase subunit M2 / ribonucleotide reductase regulatory subunit M2
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 47564890
Gene end: 47571808
  
Corresponding Affymetrix probe sets: Dr.1691.1.S1_at (Zebrafish Array)   NM_131450_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130566
Ensembl peptide - ENSDARP00000140264
Ensembl peptide - ENSDARP00000135447
Ensembl peptide - ENSDARP00000132824
Ensembl peptide - ENSDARP00000103553
NCBI entrez gene - 30733     See in Manteia.
RefSeq - NM_131450
RefSeq Peptide - NP_571525
swissprot - A0A0R4ICB4
swissprot - G3G7U0
swissprot - P79733
swissprot - A0A0R4ILJ6
swissprot - A0A0R4ID34
ZFIN ID - ZDB-GENE-990415-25
Ensembl - ENSDARG00000078069
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000016442Gallus gallus
 AC007240.1ENSG00000284681Homo sapiens
 RRM2ENSG00000171848Homo sapiens
 Rrm2ENSMUSG00000020649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rrm2 / P79733 / ribonucleotide reductase M2 polypeptide / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *ENSDARG00000020711100
rrm2b / ribonucleotide reductase M2 b / Q7LG56* / Q6PEE3* / ribonucleotide reductase regulatory TP53 inducible subunit M2B* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rr...ENSDARG0000003336765


Protein motifs (from Interpro)
Interpro ID Name
 IPR000358  Ribonucleotide reductase small subunit family
 IPR009078  Ferritin-like superfamily
 IPR030475  Ribonucleotide reductase small subunit, acitve site
 IPR033909  Ribonucleotide reductase small subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0009263 deoxyribonucleotide biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005971 ribonucleoside-diphosphate reductase complex IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000109 forebrain forebrain commissural neuron axon guidance disrupted , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle distended , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II shape , abnormal
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 ZFA:0001094 whole organism whole organism curved dorsal , abnormal
whole organism viability , abnormal
whole organism shape , abnormal
whole organism bent , abnormal
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 ZFA:0001115 trunk trunk necrotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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