ENSDARG00000033367


Danio rerio

Features
Gene ID: ENSDARG00000033367
  
Biological name :rrm2b
  
Synonyms : ribonucleotide reductase M2 b / rrm2b
  
Possible biological names infered from orthology : Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b), transcript variant 3, mRNA. / Q6PEE3 / Q7LG56 / ribonucleotide reductase regulatory TP53 inducible subunit M2B
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 32916372
Gene end: 32928486
  
Corresponding Affymetrix probe sets: Dr.23801.1.A1_at (Zebrafish Array)   NM_001007163_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000050749
Ensembl peptide - ENSDARP00000113482
NCBI entrez gene - 368909     See in Manteia.
RefSeq - NM_001007163
RefSeq Peptide - NP_001007164
swissprot - Q7ZYW0
ZFIN ID - ZDB-GENE-030616-614
Ensembl - ENSDARG00000033367
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RRM2BENSGALG00000040921Gallus gallus
 RRM2BENSG00000048392Homo sapiens
 Rrm2bENSMUSG00000022292Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rrm2 / P79733 / ribonucleotide reductase M2 polypeptide / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *ENSDARG0000007806972
rrm2 / P79733 / ribonucleotide reductase M2 polypeptide / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *ENSDARG0000002071172


Protein motifs (from Interpro)
Interpro ID Name
 IPR000358  Ribonucleotide reductase small subunit family
 IPR009078  Ferritin-like superfamily
 IPR030475  Ribonucleotide reductase small subunit, acitve site
 IPR033909  Ribonucleotide reductase small subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0009263 deoxyribonucleotide biosynthetic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005971 ribonucleoside-diphosphate reductase complex IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014017 rrm1 / ribonucleotide reductase M1 polypeptide / P07742* / P23921* / ribonucleotide reductase catalytic subunit M1* / Ribonucleoside-diphosphate reductase large subunit *  / complex
 ENSDARG00000044125 txn / thioredoxin / Txn1* / Q6A555* / Q86VQ3* / TXNDC8* / P10599* / P10639* / Q69AB2* / TXNDC2* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 8* / thio...  / reaction
 ENSDARG00000033367 rrm2b / ribonucleotide reductase M2 b / Q7LG56* / Q6PEE3* / ribonucleotide reductase regulatory TP53 inducible subunit M2B* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rr...  / complex
 ENSDARG00000031435 zgc:56493 / TXN* / Txn1* / Q6A555* / Q86VQ3* / P10639* / Q69AB2* / TXNDC2* / TXNDC8* / P10599* / thioredoxin* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain contai...  / reaction






 

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