ENSGALG00000040921


Gallus gallus

Features
Gene ID: ENSGALG00000040921
  
Biological name :RRM2B
  
Synonyms : ribonucleotide reductase regulatory TP53 inducible subunit M2B / RRM2B
  
Possible biological names infered from orthology : Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b), transcript variant 3, mRNA. / Q6PEE3 / Q7LG56
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 129686126
Gene end: 129700944
  
Corresponding Affymetrix probe sets: GgaAffx.10231.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052479
NCBI entrez gene - 420253     See in Manteia.
RefSeq - XM_418364
swissprot - A0A1D5PI47
Ensembl - ENSGALG00000040921
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rrm2bENSDARG00000033367Danio rerio
 RRM2BENSG00000048392Homo sapiens
 Rrm2bENSMUSG00000022292Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRM2* / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *ENSGALG0000001644275


Protein motifs (from Interpro)
Interpro ID Name
 IPR000358  Ribonucleotide reductase small subunit family
 IPR009078  Ferritin-like superfamily
 IPR012348  Ribonucleotide reductase-like
 IPR030475  Ribonucleotide reductase small subunit, acitve site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0003014 renal system process IEA
 biological_processGO:0006264 mitochondrial DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0009200 deoxyribonucleoside triphosphate metabolic process IEA
 biological_processGO:0009263 deoxyribonucleotide biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000040921 RRM2B / ribonucleotide reductase regulatory TP53 inducible subunit M2B / Q6PEE3* / Q7LG56* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b), transcript variant 3, mRNA.*  / complex
 ENSGALG00000017350 RRM1 / ribonucleoside-diphosphate reductase large subunit / P07742* / P23921* / ribonucleotide reductase catalytic subunit M1*  / complex
 ENSGALG00000015704 TXN / P08629 / Thioredoxin / Txn1* / TXNDC2* / P10599* / P10639* / Q86VQ3* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 2 (spermatozoa)*  / reaction






 

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